.Dangers of Dietary Isoflavones, Soy and Others

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

http://www.mayanmajix.com/soy.html - Dangers of Soy

“Soy - Abundance Of Health Hazards”

http://www.mayanmajix.com/soy01.html

May 2003 – November 2004

April 2006

                                                                                                                                                                                                  Page 1 of - over 144 pages

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                Cargill has received “self-determined” GRAS status, not approved U.S.A. FDA GRAS status, for its AdvantaSoyTMClearTM isoflavone supplement to be used as an additive for beverages, nutrition bars, yoghurt, meal replacements and confections.  The summaries of abstract studies, the evidence, attached here give ample demonstration of the real dangers to the general public of adding phytoestrogens (isoflavones) to common foods, as well as, exposing the very real dangers imposed onto the general public by the soy and the food industries Self Regulation”, “Economic Self Interest”, and the risks of abandoning “The Precautionary Principle.”

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This collection of scientific research abstracts, ( the evidence ), out of a continually growing list of hundreds available, represents a fast growing body of scientifically creditable medical and dietary research on the many serious health hazards, (including cancer), of putting soy & soy ingredients in our food supply.  Almost all of the abstracts presented here are also published in the NIH Medline PubMed data base and are representative of current and past research from around the world, in 2004 and going back to 1916, 1911, even as far back as 1907.  Full research is also available via these abstracts.  Notice some of the research studies include those from the US Department of Energy and NCTR which are Federally operated and funded, and other very reputable research institutions from around the world. 

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              This collection of scientific research abstracts is from well-designed studies, from around the world, conducted in a manner which is consistent with generally recognized scientific procedures & principles which show that there does exist significant scientific agreement among experts from around the world, [qualified by scientific training, experience and expertise], a very strong statistically significant association of harm to human and to animal health from the consumption of soy, soy protein, and soy estrogen ingredients in our food supply and an INCREASED RISK of a variety of cancers and other major and life threatening health problems, referred to in this body of evidence as Hidden Harm,” which includes but not limited to this list of known, ignored and still denied Side-Effects of ... endocrine disruption ... thyroid suppression ... immune system suppression ... heart disease ... liver disease ... leukemia, (IAL) ... Cancer(s) - breast, bone, uterine, liver, colon, pancreas, thyroid etc ... Arthritis ... infertility / lower sex drive ... growth problems ... subtle changes in sexually dimorphic behaviors ... Osteoporosis ... learning disabilities & Alzheimer’s / Parkinson’s Disease from Brain / Nervous System damage ... chromosome fragmentation & errors in chromosome orientation ... DNA damage ... “DEATH”.  Note: Genistein in soy is also a Topoisomerase II-poison pages, 32, 44. Read testimonials on pages 15 to 20, 100, 116, 117, and 122 – 126.

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                See page 121 for a more detailed list of ignoredhealth hazards associated with eating soy, which are also being called “adverse medical and developmental conditions.”  For taking “legal action” against the manufactures and sellers of soy products regarding developing these medical problems while eating soy, see pages 120, 4-7, 10, 18 and 97-119.  For some of the history on how and why soy got into our food supply, and why soy is still in our food supply, see pages 4, 5, 11, 12, 18, 105.  Now, see the evidence,” the proof of harm, which includes but is not limited to the over 205 scientific research abstracts from around the world between 1907 into 2004 on pages 29 - 84 and also read what everyone can do about it on pages 118 and 142. This research paper will reveal and easily prove why the addition of isoflavones to common foods have always posed a clear & extreme danger to the public and should not be allowed.

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                It has been argued that high levels of soy isoflavones such as genistein, daidzein and genistin in Asian diets protect the inhabitants of Japan and China from certain degenerative diseases, especially breast and prostate cancer.  Actually, consumption of soy in traditional Asian diets is low.  A 1975 report lists soyfoods as minor sources of protein in Japan and China.(1.)  Major sources of protein listed were meat including organ meats, poultry, fish and eggs.  Average isoflavone consumption in Asian diets ranges from 10-28 mg/day, as shown in the table below.  Studies indicate that isoflavone consumption at levels slightly exceeding those found in tradition diets results in thyroid suppression and endocrine disruption.  The AdvantaSoyTMClearTM supplement would add 30-50 mg of isoflavones to a 100-gram serving of various common foods, levels that exceed the amounts found in traditional diets and that are in the range of levels shown to cause problems, especially for sensitive individuals.  It is not only possible but likely that many individuals will consume two or more servings of foods to which the Cargill isoflavones have been added, especially as these foods will be promoted with much advertising touting their health benefits.  Two or more servings of such foods would provide 60-100 mg isoflavones per day, an amount that clearly poses dangers after only a brief period of daily intake.

                                                                                                                                                                                                      Isoflavones

      China (1990, 1999 survey), (5.)                                                                                                                                                3  mg/day

      Japan (1996 survey), (2.)                                                                                                                                                        10  mg/day

      Japan (1998 survey), (3.)                                                                                                                                                        25  mg/day

      Japan (2000 survey), (4.)                                                                                                                                                        28  mg/day

      In Japanese subjects receiving adequate iodine, Soy still causes thyroid suppression after 3 months use,(6.)     38  mg/day

      In American women, causing hormonal changes, after 1 month, (7.)                                                                            45  mg/day

      AdvantaSoyTMClearTM.                                                                                                                             30-50 mg / 100 g serving      … / 2

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Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

.

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As evidence on toxicity of soy isoflavones accumulates, warnings have begun to appear in the popular press. An article appearing in the Washington Post Health Section was titled: “You have to be soy careful: tofu and similar foods may be beneficial, but some experts fear that too much could be unsafe.”(8.)  Writing for the New York Times, health columnist Marian Burros published the following: “Against the backdrop of widespread praise ... there is growing suspicion that soy-despite its undisputed benefits-may pose some health hazards ... Not one of the 18 scientists interviewed for this column was willing to say taking isoflavones was risk free”(9.) .  

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References: ( Parts of page 1 are from an earlier draft version. Up-date at http://www.westonaprice.org/soy/dangersisoflavones.html )

1.   Nutrition during Pregnancy and Lactation. California Department of Health, 1975.

2.   Fukutake M, Takahashi M, Ishida K, Kawamura H, Sugimura T, Wakabayashi K. Quantification of genistein and genistin in soybeans

      and soybean products. Food Chem Toxicol 1996;34:457-461.

3.   Nagata C, Takatsuka N, Kurisu Y, Shimizu H. Decreased serum total cholesterol concentration is associated with high intake of soy

      products in Japanese men and women. J Nutr 1998 Feb;128(2):209-13.

4.   Nakamura Y, Tsuji S, Tonogai Y. Determination of the levels of isoflavonoids in soybeans and soy-derived foods and estimation of

      isoflavonoids in the Japanese daily intake. J AOAC Int 2000;83:635-650.

5.  This exhaustive study of Chinese diets found that legume consumption ranged from 0 to 58 grams per day, with a average of 13 grams

      According to the researchers, about 2/3’s of this was supplied by soy beans, giving average consumption of about 9 grams of soy

      products per day. Chen J, Campbell TC, Li J, Peto R. Diet, Lifestyle and Mortality in China. A study of the characteristics of 65

      counties. Monograph, joint publication of Oxford University Press, Cornell University Press, China People's Medical Publishing

      House, 1990. Isoflavone content is estimated be about 3 mg per day based on an average amount of 30 mg total isoflavones per 100

      grams of tofu. USDA-Iowa State University Database on the Isoflavone Content of Foods 1999.

6.  Y Ishizuki, et al, “The effects on the thyroid gland of soybeans administered experimentally in healthy subjects,” Nippon Naibunpi

      Gakkai Zasshi 1991, 767: 622-629

7.   Cassidy A, Bingham S, Setchell KD. Biological effects of a diet of soy protein rich in isoflavones on the menstrual cycle of

      premenopausal women. Am J Clin Nutr 1994;60(3):333-340.

8.   Washington Post Health Section, January 30, 2001. 

9.   Burros M. Doubts Cloud Rosy News on Soy. New York Times, January 26, 2000.  

 

As you read through this paper you will soon discover,

Soy acts like a fertilizer and fertilizes, feeds, cancer cells causing them to grow.

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                “... Propaganda ... “is the systemic propagation of a given doctrine or of allegations reflecting its views and interests; material disseminated by the advocates of a doctrine."  The promotion of soy as a miracle food has been both systematic and reflective of the doctrine of the food industry — that imitation foods are good for us and traditional foods are unhealthy.  The soy campaign is, in fact, a case study in the use of propaganda to promote commercial interests,” ( Profits from a known & proven poisonous food ingredient above the Health, Safety and the Well-being of everyone, world wide ).  Quote from http://www.mercola.com/2001/apr/7/soy.htm .

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                “Strong and Wrong” - virus - “Weak and Right” ...  The soy industry ... one of the world’s most wealthy, influential and powerful business organization ... funds millions of dollars of soy research and advertising each year in order to increase sales; so, what chance is there for discoverers of soy toxins to get funding to continue their work of exposing the truth about the many serious and deadly health hazards of eating soy ??. Soy Politics, new link at http://www.soyonlineservice.co.nz/05soypolitics.htm the old link at http://www.soyonlineservice.co.nz/politics.htm The soy industry's influence over the media, research institutions and government agencies is strong.  The goal of soy research is to boost industry profits and the US economy. 

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“Education is the most powerful weapon you can use to change the world,” by Nelson Mandela. We, the volunteers of Soy Online Service, uncover soy’s many serious & sometimes deadly health hazards, as well as, soy industry’s intense influence and political corruption that allows soy and soy ingredients in our food supply to illegally stay on the market world wide.

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“… All Truth Passes Through 3 phases: first it is ridiculed; next it is violently opposed; and finally it is accepted as self evident …”, by the German philosopher Arthur Schopenhauer.

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 i  i  i , i  i  i , i  i  i , i  i  i , (+) i  i  i - See page 96 for abstract summary.

   - http://www.soyonlineservice.co.nz/articles/Soyatox.htm .

1994    “Purification and physico-chemical characterization of soyatoxin, a novel toxic protein isolated from soybeans (Glycine max),” – Vasconcelos I.M., Trentim A, and others, Arch Biochem Biophys 1994 Aug 1 312:2 357-66, Department Of Biochemistry and Molecular Biology, Unversidade Federal do Ceara, Fortaleza, Brazil.

                                                                                                                                                                                                                          ... / 3

- 3 –

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

Also see pages 84, 127, “…It may not be coincidental that Pancreatic Cancer recently moved up to 4 th place as cause of cancer deaths in men & women in the USA as consumption of soyfoods in the US has increased.  In the 1970’s and 1980’s, several researchers studying protease-inhibitor damage on the pancreas noted that pancreatic cancer had moved up to 5 th place, wondered if there might be a soybean-protease inhibitor connection…”, taken from page 43 of the Weston A Price Foundation’s 50 page petition of objection to the FDA, June 14, 2004, at ( # 2004Q-0151 ), regarding a request by The Solae Corp. asking FDA to issue a Health Claim saying that soy prevents cancer

 

The Doctor Within

“The Magic Bean? Soy-Taintly Not !.”

. http://thedoctorwithin.com/index_fr.php?page=articles/magic_bean.php .

Old Link www.thedoctorwithin.com/articles/magic_bean.html .

 

Soy protein isolate is big business.  One of the biggest producers of soy protein is Protein Technologies International of St. Louis, a DuPont subsidiary. (Finucan)  We must appreciate the brilliance of taking a waste product from an already extremely processed food source and getting the majority of the population to think of this dead by-product as a food staple.

 

In general, the vast majority of soy products today are examples of a super-refined artificial food, devitalized, and devoid of nutritional value.  It is a true food of commerce, as Royal Lee would have said.

 

THE GOLDEN BEAN

Why doesn't anyone know about all this ??.  How can we go from a perfect food to a non-food and have 99% of the population know nothing about it ??.  When this familiar scenario appears, it always means one thing: time to follow the money.

 

In that regard, here's some interesting statistics: Today, the soybean is America's 3rd largest crop (harvesting 73.8 million acres in 2002), supplying more than 50 percent of the world's soybean demand. (Soy Stats Reference Guide, 1999, also Bernard)

.........................................................

 

US Soybean                            US Soybean                                      US Soybean

Production in millions of bushels      Crop Value                                  Oil Production

                        1940 - - -      78                       1971 - - - $   3.56 billion                     1996 - - - over 6 million tons  

                        1971 - - - 1,176                       2002 - - - $15 billion                                           (1997 Soy Stats)

                        2002 - - - 2,730

                                                                                                            - source: 2002 Soy Stats Reference Guide

 

By 2002, crop value is $15 billion per year.  Keep in mind, this figure does not take into account the retail market of the dozens of finished soy food products sold in supermarkets.  That total probably approaches $100 billion.  It's not just in the soyburgers and margarine and cooking oil and soy milk.  For well over 20 years, in many, many other processed foods, we often get a …

… HIDDEN SURPRISE …

See a list of foods with soy ingredients ... pages 18 and 121

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i      ;      i

 

“The Truth About The Drug Companies” ... $ ... http://www.nybooks.com/articles/17244?email ... 12 page essay

— by Marcia Angell, a former editor of the New England Journal Of Medicine.

— The New York Review of Books, Volume 51, Number 12, July 15, 2004.

— "... The most startling fact about 2002 is that the combined profits for the 10 drug companies in the Fortune 500 ($35.9 billion) were more than the profits for all the other 490 businesses put together ($33.7 billion).(12) ...”.

---  “... When I say this is a profitable industry, I mean really profitable.  It is difficult to conceive of how awash in money big pharma is ...".                                                                                                                                                                                  ... / 4

- 4 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

The Newest Research On Why You Should Avoid Soy

by Sally Fallon and Mary Enig PhD., 2000 ... http://www.mercola.com/article/soy/avoid_soy.htm

 

 

“... The propaganda that has created the soy sales miracle is all the more remarkable because, only a few decades ago, the soybean was considered unfit to eat - even in Asia.  During the Chou Dynasty ( 1134 - 246 BC ) the soybean was designated one of the five sacred grains, along with barley, wheat, millet and rice.

 

“... However, the pictograph for the soybean, which dates from earlier times than the Chou Dynasty, indicates that it was not first used as a food ; for whereas the pictographs for the other four grains show the seed and stem structure of the plant, the pictograph for the soybean emphasizes the root structure.  Agricultural literature of the period speaks frequently of the soybean and its use in crop rotation.  Apparently the soy plant was initially used as a method of fixing nitrogen”. 13.

 

“... The soybean did not serve as a food until the discovery of fermentation techniques, some time during the Chou Dynasty.  The first soy foods were fermented products like tempeh, natto, miso and soy sauce. At a later date, possibly in the 2nd century BC, Chinese scientists discovered that a purée of cooked soybeans could be precipitated with calcium sulfate or magnesium sulfate (plaster of Paris or Epsom salts) to make a smooth, pale curd - tofu or bean curd.  The use of fermented and precipitated soy products soon spread to other parts of the Orient, notably Japan and Indonesia ...”.

 

“... The Chinese did not eat unfermented soybeans as they did other legumes such as lentils because the soybean contains large quantities of natural toxins or "anti-nutrients".  First among them are potent enzyme inhibitors that block the action of trypsin and other enzymes needed for protein digestion ...”.

 

“... These inhibitors are large, tightly folded proteins that are not completely deactivated during ordinary cooking. They can produce serious gastric distress, reduced protein digestion and chronic deficiencies in amino acid uptake.  In test animals, diets high in trypsin inhibitors cause enlargement and pathological conditions of the pancreas, including cancer ...”. 14.

 

“... Soybeans also contain haemagglutinin, a clot-promoting substance that causes red blood cells to clump together. Trypsin inhibitors and haemagglutinin are growth inhibitors. 

 

“... Soy advertisers selectively claim lower rates of reproductive cancers for Japanese and Asians eating soy, while ignoring the fact that these same people also have much higher rates of cancer of the ... esophagus ... stomach ... liver ... pancreas ... and thyroid ... particularly as soy causes these same types of cancers in laboratory test animals. 37-39

 

“... Japanese and Asians eat soy in very small amounts, as a condiment (a seasoning), not as a protein substitute, not as a replacement for animal foods !.  42.

 

“... Soy protein has not been given USA GRAS (Generally Recognized As Safe) status or pre-market approval  because of its carcinogenic properties. 72.   It is not even legal to add it to our food.

 

Note: Make sure the label on your vitamins, minerals, and medications says contains no Soy or … contains no Soy ingredients .

                                                                                Pet Food, farm animal foods                                                                                         ... / 5

- 5 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

Soy Warning Labels, For Medical Reasons

Two of The USA F.D.A.’s Expert Scientists Protest Soy Approval.

 

                Researchers and Whistle-blowers Daniel Doerge Ph.D and Daniel Sheehan Ph.D are two of the U.S.A.’s  Food and Drug Administration’s, FDA, expert scientists on soy who signed a Feb. 18, 1999 letter of protest to the FDA when the FDA granted soy a “health claim” in 1999.  This letter expresses serious concerns regarding the perceived safe use of soy, if soy was to be granted a “health claim,” and includes 26 documented scientific referenced studies, (Abstracts), that show a link between eating soy and serious health problems. 

 

          In their letter of protest they said, “… it is inappropriate to allow a health claim for Soy Protein Isolate, SPI, … it could be misinterpreted, … the health labeling of SPI for foods needs to be considered just as would the addition of any Estrogen orGoitrogen to foods, which are bad ideas.  Estrogenic and goitrogenic drugs are regulated by the FDA, and are taken under a physician’s care.  Patients are informed of risks, and are monitored by their physicians for evidence of toxicity.

          No similar safeguards are in place for foods, so the public will be put at potential risk from soy isoflavones in SPI without adequate warning and information...”

See letter ... http://abcnews.go.com/onair/2020/2020_000609_soyfdaletter_feature.html, article withdrawn,

and at ... http://www.mercola.com/2001/jun/30/soy_fda.htm ,  use Google Search for more.

 

 

Toxic Load means that the risk is a function of  dose length, dose strength, and of the physical condition of the consumer. Reference:

“The Dose Makes the Poison: A Plain-Language Guide to Toxicology”, 2nd Edition, ©  1996, by M. Alice Ottoboni,

          “Chemical Carcinogens", © 1976, by The American Chemical Society,

          “Principles of Toxicology”, by Casarett and Doull,

          “The Basic Science of Poisons”, © 2001, Casarett, Amdur, Klaassen, Doull  

 

The Soy industry has “applied twiceand wasturned down twice(1979, 1999) on both of its applications for “GRAS (Generally Recognized As Safe)” status for Soy Protein BECAUSE of Soy’s carcinogenic properties; also Soy has not been given “Pre-market Approval” for its use in our food.  It is not even legal to add it to our food.  In addition, Soy is in breach of, in violation of - “WHO/CODEX - Food Safety Standards.”  P.S.  To add insult to injury, Soy fails the 1958 “Delaney Amendment to the USA’s FDA Reg.’s which prohibits the use of any food additive if it is found to cause cancer in any animal species or in man, at any dose level ... http://www.pcdf.org/meadows/delaney.htm .  Add these 6 strikes against the Soy industry to the growing list of ignored side-effects on page 1., and you have millions of crime scenes.  In the US FDA’s Poisonous Plant Database” … http://vm.cfsan.fda.gov/~djw/pltx.cgi?QUERY=SOY ... Soy, and (Flax and Linseed), and (Canola, and Rapeseed) are all listed as “poisonous plants”, and the FDA recommends that if you are injured by them, to contact your local Poison Control Center in your area, (at ... http://www.aapcc.org/.), or call 911.  Soy acts like a fertilizer and fertilizes, feeds, cancer cells to help them grow.                 ... / 6

- 6 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

 

 

Why” Soy Protein - Is In Breach of - WHO/Codex Standards

http://www.soyonlineservice.co.nz/Refs/Codex.htm old Link

  http://www.soyonlineservice.co.nz/articles/Codex.htm New Link to new website format

World Health Organization, WHO

 

 

 

WHO/Codex General Standards for Soy Protein Products

 

WHO/Codex Standard 175-1989

6.3 (c)  When tested by appropriate methods of sampling and examination, the product shall not contain other poisonous substances which may represent a hazard to health.

 

 

WHO/Codex General Guidelines for the Utlization of Vegetable Protein Products (VPP) in Foods CAC/GL 4-1989

 

                4.1  VPP intended for human consumption should not represent a hazard to health.

 

                Annex  

                .               The raw materials from which VPP are produced may contain naturally occurring toxic or anti-nutritional factors. Some of these factors may still be present in VPP after processing. In the light of the above observations it becomes important that prior to the use as human food, VPP be subjected to adequate testing to demonstrate safety and appropriate nutritional quality. A distinct VPP needs to be tested pursuant to this guideline only once, that is, to obtain a toxicological and nutritional profile for VPP. Prior history of safe use may be taken into account in the evaluation of a novel VPP proposed for general consumption, but this alone is not necessarily sufficient to preclude adequate pre-clinical testing by currently available, more objective, laboratory animal feeding studies, and, where applicable, studies using human volunteers.

 

                1.4  Toxicological Safety:

The safety of the VPP should be predicted from information concerning methods of production, chemical and physical properties. This should be supported, where necessary, by safety data using laboratory animals.

 

                2.4.1  Subacute Toxicity Studies:

The purpose of these studies is to delineate the toxic potential of VPP and to elucidate such problems as species sensitivity, the nature of gross and micro-pathological changes and the approximate dose level at which these effects occur. They also provide guidelines for the selection of dosage for chronic toxicity tests and any functional or biochemical studies that may be necessary.

 

                2.4.1.3  Length of Study:

                Subacute toxicity feeding trials should be at least three months duration.

 

                2.4.2  Other Studies: 

Following an appraisal of the source and the method of manufacture of the VPP together with the results of nutritional and subacute toxicity studies, the need for further studies including chronic, reproduction, teratogenic and mutagenic studies will be evaluated.

 

SOS comment: There is clear evidence that Soy Protein does not meet WHO/Codex Guidelines.

 

 

 

                                                                                                                                                                                                                          ... / 7

- 7 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandonging “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

The Isoflavones Present In Soy Protein Induce-(cause):

( “Why” Soy Protein - Is In Breach of - WHO/Codex Standards )

Continued

 

Subacute toxicity http://www.soyonlineservice.co.nz/04thyroid.htm .  Phytoestrogens Anti-thyroid agents

 

Chronic toxicity http://www.soyonlineservice.co.nz/articles/Brain.htm .  Abstracts (3)

                                -  i  i  i , i  i  i , i  i  i , i  i - Also see ... Frying the Brain With Soy ... page 63

                1996    “Association of mid-life consumption of tofu with late life cognitive impairment and dementia: the Honolulu-Asia Aging Study,” - White L, Petrovich H, and others, Fifth International Conference on Alzheimer's Disease, #487, 27 July 1996, Osaka, Japan.

— There is evidence suggesting that estrogens modulate neural and synaptic plasticity during aging.

— “... We found an association of consistently high levels of tofu consumption in mid-life with low cognitive test scores (p=0.02) and (independently) with Alzheimer's disease in late life, controlling for all other relevant variables.  The odds ratio for AD in persons who reported eating tofu at least twice weekly was 2.4 (95% CI 1.14-5.09), compared with persons reporting tofu consumption rarely or never ...”.

 

Reproductive toxicity http://www.soyonlineservice.co.nz/04infertility.htm .  Phytoestrogens, Nature’s contraceptives.

Reproductive system damage … Phytoestrogens can make animals intertile, what about People ??.

 

Teratogenic effects http://www.soyonlineservice.co.nz/articles/Bdefects.htm .  The Dominion, Feb 21, 2000,

                Embryo, monster makingDeformities Found in Sons of Vege Mums.

 

Mutagenic effects http://www.soyonlineservice.co.nz/articles/metzler.htm .  Immune System Effects

                                         http://www.soyonlineservice.co.nz/04immunefunction.htm .

                ( 9+ ) Abstracts -  i  i  i , i  i  i , i  i  i , i  i  i -

Causes cancer cells to grow ... DNA damage ... chromosome fragmentation and errors in chromosome orientation.

 

The potential oral hazard of phytoestrogens - has long been known - by food regulator such as the FDA.  During his presentation at the 3rd International Phytoestrogen Conference in 1995, FDA regulator Dr Michael Bolger made direct reference to the soy isoflavones causing infertility, uterine hypertrophy and testicular atrophy in rodents, liver disease and reproductive failure in cheetah and menstrual cycle effects on women.  ( Also, see bottom of page 8 … the TRUTH about Fermented Soy ).

*      *      *

 

Two Books

That Expose and Unmask The Corrupt Soy Industry

 

http://www.wholesoystory.com/About_the_Whole_Soy_Story.html ...The Whole Soy Story,” by Kaayla T. Daniel, MS, Ph.D, CCN.  With 30 chapters & 7 subsections, new 2004 book tells the whole truth about soy, its many very serious health hazards, & real history of how soy got into our food supply.  It is all about fact and not fiction.  This book presents and interprets the often contradictory evidence on soy and disease to determine what studies are valid, which justify hope, which are mere hype – and why, with a FAQ section.

“It is child abuse to feed a baby soy formula.”

http://www.doctorsaredangerous.com/index.html ... Take Control of Your Health & Escape the Sickness Industry,” by Elaine Hollingsworth reveals in Chapter 9 ... Soy - The Abominable Bean, at ....

http://www.doctorsaredangerous.com/ChapterNine.pdf  … just how we’ve been all conned because of corporate greed, bad science, and regulatory misconduct by most governments around the world.  It explains how eating soy foods produces many very serious health hazards like cancer, it destroys your thyroid and leaches calcium from your bones (osteoporosis), and also why “It is child abuse to feed a baby soy formula.”  All this and a whole lot more.                                                                                                                                   ... / 8

- 8 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/ .

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

Want to Reduce Breast Cancer ?.  Fish Oil is a Must

... http://www.mercola.com/2002/jun/5/fish_oil.htm ...

June 5, 2002

 

“... Differences in the actions of Omega-3 fats and Omega-6 fats have been observed on these genes.

                      ** Omega-3 fats ... have been described to "reduce" cancer cell growth, ( includes Fish Oils ) ...

                        * Omega-6 fats ... have been found to "cause" cancer growth ...”.

 

*Omega-6 oils, “... I strongly recommend avoiding ... sunflower ... corn ... Soy ... safflower ... Canola ... or products that contain these oils.  In other words, no hydrogenated or partially hydrogenated fats including ... margarine ... vegetable oil ... (vegetable)-shortening ... etc.  These oils are full of Omega-6 fats and will only worsen your Omega-6 / 3 ratios ...”.  Soy – (Flax, Linseed) – (Canola, Rapeseed) – are all listed in the FDA’s Poisonous Plant database ... http://www.cfsan.fda.gov/~djw/plantox.html .  Over 685 scientific research abstracts listed, out of over 1,000 known, going way back to 1850, proving serious harm to human - animal health. (over 400 such abstract do exist for soy alone since 1907) Soy industry, food, health food industries and governments have all been lying to us, pages 5, 6. 7, 113, 119, 121 ... abstracts pages 29 – 96

 

**Omega-3 oils, (EPA, DHA),“... Acceptable oils are high quality ... extra virgin “olive oil” ... “Coconut oil” ... “avocados” ... “organic butter” ... better yet ... “Grass-fed organic butter ...”.  (ALA) in Flax causes prostate cancer cells to grow http://www.mercola.com/2004/jul/21/flax_seed_oil.htm … and … http://www.ajcn.org/cgi/content/abstract/80/1/204 .

 

“... Generally our diet contains far too many omega-6 fats.  Experts looking at the dietary ratio of omega-6 to omega-3 fatty acids suggest that in early human history the ratio was about 1:1 ... ... Currently most Americans eat a dietary ratio that falls between 20:1 and 50:1.  The optimal ratio is most likely closer to the original ratio of 1:1 …”. 

 

“... For most of us, this means greatly reducing the omega-6 fatty acids, & increasing the amount of omega-3 fatty acids we eat ...”.

                                                                                                *      *      *

.

Fermented Soy ... Cancer Chemo-preventative ??

( Also see pages 5 - 7, 10, 21, 29, 31, 32, 36, 42, 48, 52, 65, 72, 74, 75, 81, 101, 104, 109, 113, 118, 121, 142 )

. http://www.mercola.com/2004/aug/4/fermented_soy.htm .

 

The soy industry’s claim that "... fermented soy products like, Natto, Tempeh, Soy Sauces, Fermented tofu and soymilk, and Miso are particularly rich in the isoflavone aglycones, genistein and daidzein, which they say are believed to be cancer chemo-preventatives ...". The implication by the soy industry is that these natural occurring chemical compounds are good, for instance in cancer prevention, if they are consumed in natto or miso (not exactly staples of Western diets), when in fact it is exactly these same chemicals that are the endocrine disrupters which have so alarmed many independent scientists around the world. Genistein in particular is fingered, was proven, by FDA scientists, S.S. Kuan, O.J. Francis, et al, at the FDA's NCTR and the New Orleans Poisonous Plants laboratories, way back in 1991, as carcinogenic, estrogenic, cytotoxic, anti-thyroid, on research lasting over 3 months, Page 126…(see 10 th World Congress Report, pg. 527)

 

But, what soy industry also KNOWS but still NEVER tells people when claiming fermented soy is chemo-preventative is ... it all depends on the dose levels of these chemicals, [even though this principle has been a basic teaching since 1500's in the science of Toxicology-(see research by the famous Swiss physician “Paracelsus ... http://www.mindfully.org/Pesticide/Paracelsus-Dose-ToxicologyOct01.htm .).]. At high chemotherapy dose levels genistein & daidzein kills cells, and cancer cells. But the dose levels needed for this chemotherapy type responses, (the soy industry claims to happen from eating fermented soy), are also at dose levels far beyond those achievable at dietary consumption levels. So, their claim of chemo-preventative has no relevance at all when it comes to consuming these chemicals at dietary levels in soy or vitamin supplements. As the scientific research clearly demonstrates, at dietary levels genistein and daidzein disrupts and damages the immune and hormone system, and also causes a variety of health problems including a variety of cancers, and DNA damage.

 

This claim by the soy industry clearly shows the fallacy of seeking and promoting short-term results and ignoring long-term consequences, administering drugs to people who don't need them, a case of hidden mass medication upon the unsuspecting and unknowing public.

 

Fermentation only lowers the toxin levels, it doesn’t eliminate them. To get the lowest toxin level, fermentation needs to be at least 2 years, as Asians do, not like in North America, where it can be shorter than 3 months, & using chemicalized fermentation methods.    ... / 9

- 9 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

.

Sunlight Actually Prevents Skin Cancer

http://www.mercola.com/2002/apr/3/sun_prevents_cancer.htm

 

 

“... Skin cancers are more likely related to the large distortion most people have in their Omega-6 and Omega-3 fat ratios ... The likeliest mechanism for a protective effect of sunlight is vitamin D, which is synthesized by the body in the presence of Ultraviolet B, UV-B ...".

 

"... Most people believe that sun exposure causes cancer.  Nothing could be further from the truth.  As this study published in the prestigious Cancer journal, March 2002, indicates, exposure to sun actually decreases cancer rates ...”.

 

“... So the solution is not to splatter sun block on. Sun block can be quite “toxic", and should be avoided by most people ...”

 

“... The sensible approach would be to limit sun exposure so you never get sunburned.  It is sunburn in conjunction with — excess  omega-6 fats — that increases your risk of skin cancer.  But even with the potential increase in skin cancer, most skin cancers are relatively benign when compared with breast, colon, and prostate cancers that lack of sun exposure is associated with ...”.

 

“... So you can't have it both ways.  Avoid the sun and don't change your diet and you will lower your risk of skin cancer, but increase your risk of far more common and deadlier cancers ... So why not change the fat content of your diet and use sensible sun exposure guidelines and reap the benefits of sunlight ?.

 

 

 

Diet and Sunlight Linked to Breast Cancer Risk

http://www.mercola.com/2002/jan/26/diet_sunlight.htm

 

"... As for the role of sunlight, researchers found an association between latitude and breast cancer, suggesting that higher UV-B exposure was protective.  UV-B rays spur the production of vitamin D in the body, it is likely the vitamin is behind the association he found in this study.  Other research suggests vitamin D may help ward off cancer ...".

 

“... Women who limit their exposure to sunshine will have lower vitamin D levels and an increased risk of breast cancer, in addition to an increased risk of osteoporosis ...".  

                                                                                                      *      *      *

References ...

 

Want to Reduce Breast Cancer ?  Fish Oil is a Must ... http://www.mercola.com/2002/jun/5/fish_oil.htm

British Journal of Nutrition, April 2002, vol.  87, no.  4, pp.  281-289(9), Abstract.

http://www.ingenta.com/isis/searching/ExpandTOC/ingenta?issue=infobike://cabi/bjn/2002/00000087/00000004&index=1&WebLogicSession=O87ckEa0teymWCWQdwK7|-1345150823091522580/-1052814329/6/7051/7051/7052/7052/7051/-1

British Journal of Nutrition, March 2002, vol.  87, no.  3, pp 193-198(6), Abstract

http://www.ingenta.com/isis/searching/ExpandTOC/ingenta?issue=infobike://cabi/bjn/2002/00000087/00000003&index=1&WebLogicSession=O87ckEa0teymWCWQdwK7|-1345150823091522580/-1052814329/6/7051/7051/7052/7052/7051/-1

 

 

Sunlight Actually Prevents Skin Cancer ... http://www.mercola.com/2002/apr/3/sun_prevents_cancer.htm

                Cancer, March 2002; 94:1867-75

 

   

Diet and Sunlight Linked to Breast Cancer Risk ... http://www.mercola.com/2002/jan/26/diet_sunlight.htm

                Cancer, January 1, 2002; 94:72-281

 

Note: Make sure the label on your vitamins, minerals, and medications says contains no Soy or … contains no Soy ingredients .

                                                                                Pet Food, farm animal foods                                                                                       ... / 10

- 10 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

Soy - “Weakens” - Your Immune System

http://www.mercola.com/2002/jun/8/soy.htm

Known still Ignored

This 2002 study funded by

“United Soy Bean Board” and the

“Illinois Council on Food & Agricultural Research”

 

 

Hormone-like compound found in Soy products, including Soy-based infant formula & menopause remedies, may impair immune function

 

When mice were injected with the plant estrogen" genistein, which is found in Soy products, levels of several immune cells dropped and the thymus, a gland where immune cells mature, shrank.

 

Of course, people eat rather than inject Soy products, but the thymus also became smaller in mice that consumed genistein in their diet. This is particularly concerning, researchers say, since the resulting blood levels of genistein in the mice were lower than those reported in human babies fed soy formula.

 

A few reports from the late 1970's and early 1980's suggested that a soy-based diet impaired infants' immune functions. About 15% of infants in the US, or roughly 750,000 children, consume soy-based formula each year.

 

Proceedings of the National Academy of Sciences , (May 21, 2002;99:7616-7621) ... see PubMed at ...

 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12032332&dopt=Abstract .

                                                     ................................................................................

 

 

Dr. Mercola’s Comment:

It is quite amazing that this study was actually published, as the findings were quite (-)negative for soy and yet it was funded by the United Soybean Board and the Illinois Council on Food and Agricultural Research.

 

Amazing, it seems that eventually the truth on soy does reach the service, despite the massive funding by the edible oil industry to convince the public that soy is the greatest thing that ever hit the planet to improve your health. See the abstract of the 1997 Lancet study at ...

                   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9217716&dopt=Abstract . 

1997    “Exposure of infants to phyto-oestrogens from soy-based infant formula,” – Setchell K.D., Zimmer-Nechemias L., Cai J., Heubi J.E., Lancet. 1997 Jul 5;350(9070):23-7., Clinical Mass Spectrometry Center, Children’s Hospital Medical Center, Cincinnati, Ohio, 45229, USA.

                                                                                                                                                                                          ... ( See bottom of page 36 )

The abstract above shows that Soy has glycosides of genistein and daidzein or plant based chemicals that mimic estrogen. They possess a wide range of hormonal and non-hormonal activities. The daily exposure of infants who consume soy formulas was 6-11 times higher than adults consuming soy foods.

 

The blood concentration of these hormones was 13,000 to 22,000 times higher than estrogen in the blood. The authors of this article speculate that this concentration may be sufficient to exert biological effects, whereas the contribution from breast-milk or cow-milk is negligible.

 

Soy formula is one of the worst foods that you could feed your child. Not only does it have profoundly adverse hormonal effects as discussed above, but it also has over 1000 % more aluminum than conventional milk based formulas

 

I don't recommend either, but if one, for whatever reason, cannot breast feed, then non-soy Carnation Good Start until six months and Carnation Follow-Up after that seem to be the best commercial formula currently available. The milk protein is hydrolyzed 80% that tends to significantly decrease its allergenicity.

                Continued ...                                                                                                                                                                                  ... / 11

- 11 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

Soy “Weakens” Your Immune System

http://www.mercola.com/2002/jun/8/soy.htm

... Continued ...

 

 

It is also important to note that when breast-feeding it is wise to avoid drinking milk as it has been shown for several decades that the milk will pass directly into the breast milk which can cause potential problems in the infant.

 

Related Articles:

Pregnant Women Should Not Eat Soy , at ... http://www.mercola.com/1999/archive/pregnant_should_not_eat_soy.htm .

Soy Formulas and the Effects of Isoflavones on the Thyroid , at ... http://www.mercola.com/2000/feb/13/soy_thyroid_disease.htm .

How Safe is Soy Infant Formula? , at ... http://www.mercola.com/2001/jun/13/soy_formula.htm .

Experts Dispute JAMA Soy Infant Formula Study , at ... http://www.mercola.com/2001/sep/15/soy_formula.htm .

Soy Milk Is Safe! That Is What the Formula Industry Says , at ... http://www.mercola.com/2001/aug/25/soy_milk.htm .

Australian Pediatric Soy Protein Formula Policy , at ... http://www.mercola.com/2001/sep/22/soy_protein_formula_policy.htm ,

                                                                        * * *      * * *      * * *

 

 

... More On Soy’s Fraudulent History ...

Also see pages 4, 5, 6, 7, 18, and 105, as well as ( 12, 100, 107, 121 )

Concerns about the potential carcinogenesis of modern soy is not new.

 

1.)  The Committee for Food Safety was worried about it in 1966, the definitive textbook “Chemical Carcinogens” published by the American Chemical Society in 1976 had a chapter titled “Plant Carcinogens” that identified soy isoflavones as known carcinogens.

2.)  The Life Sciences Committee of FASEB in its 1978-9 “Evaluation of Soy Products for Human Consumption” for the Food and Drug Administration (SCOGS-101 under contract to the FDA # 223-75-2004) declined GRAS determination because of the risks of carcinogenic ... nitrosamines ... lysinoalanines ... and nitrite occurring during the modern processing. (Not to mention the other scientifically documented natural occurring carcinogenic chemicals is soy called genistein and daidzein ).

3.)  Moreover in 1999, an application by Archer Daniels Midland Corp for GRAS determination  of GRAS (GRN 00001) for isoflavones was declined due to the failure of the applicant to reveal health risks.

4.)  Soy protein does not have GRAS determination.  Soy protein was slipped into the food chain about 1959 even though the developmental research (funded by ADM and Mead Johnson) demonstrated that it caused serious infertility problems in laboratory rats and their offspring.  This is recorded in a series of papers in the Journal of Nutrition” by Schultze, Liener et al in the 1950's  The only evaluation was in 1979 by the Life Sciences” section of FASEB, and soy protein failed because of the risk of nitrosamines forming in the heat treatment. FASEB assumed the heat treatment was removing the natural poisons and did not evaluate their safety at all.  You will find a fuller discussion of GRAS in the Home Page of www.soyonlineservice.co.nz "Trouble for Soy Protein", including Dr Fitzpatrick's opposition to the grant of health claim labelling by the FDA.  The material in http://www.soyonlineservice.co.nz/06doses.htm "Doses Simplified" gives an idea of how toxic the levels of isoflavones are in the products.

5.)  http://www.soyonlineservice.co.nz/04cancer.htm . (Phytoestrogensn – Cancer) ... Why does the Soy Online Service Webmaster, Dr. Mike Fitzpatrick PhD, an environmental toxicologist and a scientist of recognized international expertise, expresses the opinion that the lowest form of life on the planet” is anyone who claims soy and isoflavones are protective against cancer ... without also revealing ... that there are numerous world wide creditable scientific research studies, (including those by US Federal Government research institutions), which show that Soy   ... 1.) damages DNA, chromosomes and the immune system,  ... 2.) cause cancer,  ... 3.) cause existing cancer cells to multiply,  ... 4.) cause non-cancerous tumors to turn cancerous ??.  Because, those that make this claim are guilty of giving false hope to millions of people, with or without cancer, by withholding and suppressing this valuable life-saving scientific information.  But even far worse than all this, those that make this claim are placing innocent consumers at a far greater risk of contracting this same horrendous disease that all consumers are afraid of and are desperately trying to avoid. I agree.

 

                Also see pages 12, and 98 – 105 – 119 – 127

                                                                                                                                                                                                                        ... / 12

- 12 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

Soy Online Service Answers 5 Questions

An Introduction: The History Of How Soy Got Into Our Food Supply

 

... This 2nd Reply is 1st ...

 

----- Original Message -----

From: Valerie & Richard James , Soy Online Service

To: Gerald Hernesmaa

Sent: Wednesday, December 10, 2003 11:29 PM

Subject: Re: Re: Urgent ... Can you help please ?? ... Need answers to these 5 questions !!

 

OK Gerald.  In brief.  ( An Introduction ... A plausible conspiracy theory consistent with known facts and the USA National Security Agency minutes.)

 

In the early 1950's the British Government was hoping to rebuild the empire that it had largely lost as a result of WW-2.  The principle used was the one that had worked in the past.   That is, to have colonies producing  raw materials for shipment to Britain for processing and re-export.  That is how Canada, NZ, Australia, Argentina and numerous others including the USA got started.

 

For West Africa, it became known as the British Groundnut.  Scheme ... grow peanuts and ship them  to the UK  for protein extraction.  The extraction plants were built in the English Midlands .

 

The CIA did not want a strong Britain again (remember the Suez canal debacle a couple years later in 1956?).  The US Dept. of Agriculture was besotted with using the toxic waste from soymeal extraction as an export and its brief was solely to promote US agriculture.  Even the laboratory was named the Northern Resource Utilisation Center at Peoria, Ill..  Agricultural exports were to be pushed...nothing less, nothing more.

 

So a connivance was fabricated.  Undercut the British peanut protein with cheap US soy meal.  LIBERTY ships were pulled out of mothballs, export subsidies were arranged, and shipments of all-American soy hit the West African beaches in 1954. The British groundnut scheme became totally uneconomic, the British government lost millions of pounds and ultimately its West African Colonies... Ghana, Nigeria, Sierra Leone.  Liberty ships were useful again at last.

 

What a coup for the US spooks!

 

There was an added bonus.  The US government, esp Dept of Agriculture scientists, knew soymeal caused infertility.  It was no secret...it was published by Chang et al for a start in 1953.  (They probably would have thought, at the time, What a win - win - win !!.  Use the US ships to promote US agriculture, reduce the blacks, protect the Georgia peanut growers and damage the British Empire all in one ploy.  How nice to send all those infertility foods to the black populace.  That all holds up.).  What they probably did not know  was that  the infertility chemical in soybeans (genistein) was also a powerful disrupter of immune systems.  It may have opened up the West Africans' immune systems to an invasion by a little known type of monkey herpes virus that we now call HIV, and its result as Acquired Immune Deficiency Syndrome.

 

It may not be all correct, but it hangs together and is historically correct per time line.  And it was postulated by a very competent biochemist in 1993.

Cheers Dick

............................................................

 

Remember ... To protect your health and your families health, be sure to read the ingredient labels on all of the foods you buy.

Also ... be very, very careful about eating in “Restaurants” and in “Hospitals”, as they do not list the ingredients in their foods.

Vegetable oil ... has not been real vegetable oil, made from a varitey of vegetables, not including soy, since the early 1970’s.  Since then it is ... either Soy” or “Canola” or both, and it rarely includes cottonseed, peanut, palm oil.  Genistein in soy is proven to be and is classified as a Topoisomerase II-poison.  

Note: Make sure the label on your vitamins, minerals, medications says ... contains no Soy ... or ... contains no Soy ingredients  ... / 13

- 13 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

(Also see ... http://www.proparanoid.com/truth.htm ... “25 Ways To Suppress Truth, The Rules of Disinformation”)

 

 

                                     5 Questions                                                         The “Answers” with this 1st reply

 

----- Original Message -----                                                                                 ----- Original Message -----

From: "H. Michael Sweeney", hms@proparanoid.com                                From: Valerie & Richard James , Soy Online Service

To: "Gerald Hernesmaa" healthwise933@shaw.ca                                         To: Gerald Hernesmaa

Sent: Tuesday, December 09, 2003 7:38 PM                                    Cc: Irvin E. Liener

Subject: Re: Urgent ... Did you receive my package containing the           Sent: Tuesday, December 09, 2003 11:34 PM

                       Soy Research Paper ... and the $10.00 USA money order   Subject: Re: Urgent...Can you help please ??...Need answers

                                                                                                                                                        to these 5 questions !!.

 

From: Mr. H. Michael Sweeney ... Yes, thank you. Just picked it up today. (mailed him a copy of our Soy Research

paper and Soy Pamphlet).  The newsletter will be mailed tomorrow, barring unexpected disaster, like runing out of ink !.

 

The soy material is another matter.  Not quite up my ally, but very interesting topically for a number of  reasons you

may not have considered.  I'm throwing these  ( 5 questions )  at you for your comments, in case you know the answers.

They are probably too left field and may leave us both wondering.

 

 

 

Questions & Answers:

 

From: Richard and Valerie James ... Hi Gerald, Ok, Will try to keep it short.  Jimmy Hoffa is not our line !, But the C I A theory is a possibility.

1)  Who knew all the negative ramifications and when did they know it?  If they knew it in the late 1950's and 60's, I'm thinking

that may be why Jimmy Hoffa got into Soy beans in a big way, I'm thinking he likely partnered with CIA to do it (see next.).

    The Soy Online Service

    Answer ... The original projects to extract the protein from left- over soymeal after oil removal were done with funding by ADM

and Mead Johnson in the early 1950's.  Results of rat -feeding trials were published in subsequent issues of the Journal of Nutrition, by M.O. Schultz et al, in around 1953/4/5.  We have those papers but they are a rotten layout and not suitable for putting on a website as they have no opening abstracts.  The rats had troubles creating baby rats and the few baby rats they created had poor reproductive performances.  A first clue that this stuff crosses generations.  It would take us a while to get to the papers for more detail and we are flat-out with other urgent stuff.  As we recall some work was at University of Minnesota and other was at the Dept of Agriculture Resource Utilisation Center, Peoria, Illinois.

 

Subsequent work was at both Peoria and the D of A facility at Albany Ca.

 

The scientists all knew they were not removing the “estrogens” or “sterols.”  That is published in a paper by Eldridge, Nash and Wolf in the 1967 Jour of Food Chemistry.  We have that here too. In fact Walter J Wolf would be high on our list of most harmful scientists in history.  There also was research in South Carolina by Carter Matrone et al on the estrogenic effects of soy on mice in the 1960's.

 

All this is in published academic papers.  The first published analysis of estrogenic content of soy protein was by Murphy in 1982, though the UK Central Veterinary lab did analysis in 1980 and compared estrogenic effects of human-use soy...16 ppb DES and 24 ppb DES in the two samples tested....with diethylstilbestrol.  You can get that in http://www.soyonlineservice.co.nz/04soy&DES.htm ..."Soy and DES" .  

                                                                                (and also at … http://www.soyonlineservice.co.nz/Refs/murphy.htm )

 

                                                                                                                                                                                                                        ... / 14

- 14 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

Questions & Answers: Cont ...

 

2)  What would be the effect of Soy on someone who was taking anti depressants (SSRIs)?  This is a CIA developed product class which I describe as an enabler for select mind control applications.  Yes, it can be beneficial for those with true mental imbalances, a normal person it makes them more susceptible to various MC attacks and programming methods.  Mn These products went into development in the mid 1960's, if I remember my dating.  Prior to that, CIA was experimenting with a WIDE range of products, including LSD (for the same purpose) and I'm wondering if that included Soy extracts or other Soy products, byproducts, or compounds.

    Answer ...    Don't know Nor does anyone else we are aware of.

 

3)  In like manner, what would be the effect of Soy be on a schizophrenic or paranoiac personality? Would it elivate, agrivate, or excentuate, be neutral, or reduce or impede the symptoms?  Same reason for asking, since certain forms of MC targeting seems to selectively focus on individuals with these personalities.  Further, targeting on 'normal' people long term produces these personalities in the end, especially when augmented with SSRIs.

    Answer ...    It would, based on the rat research that is published, send them into low-earth orbit.  A major windup and is confirmed by numerous parent-anecdotes.  The aggressiveness has been almost beyond control. Here's a recent one ...

                                . http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12618915&dopt=Abstract .

                                2003    “The soya isoflavone content of rat diet can increase anxiety and stress hormone release in the male rat,” – Hartley D.E., Edwards J.E., and others,  Psychopharmacology (Berl) 2003 Apr 5; 167(1):46-53. Epub 2003 Mar 05.,  Psychopharmacology Research Unit, Centre for Neuroscience, Hodgkin Building, Kings College London, Guy's Campus, SE1 1UL, London, UK. david.2.hartley@kcl.ac.uk

 

We had it in our family too.  Teenagers at a time of hormonal change are most vulnerable.  In fact the peripubertal time is a risk age that was identified by Clarkson, Anmthony and Hughes et al in a paper published in 1995.

 

4)  Where does  Eli Lilly  stand  with  respect  to  anything  Soy - any participation, studys, products, etc?  They were very connected to early MC work and to the Bush family.

    Answer ...  Eli Lilley is not into soy, soy supplements or drugs with pseudo-soy chemicals.......as far as we know

 

5)  Are you aware of any military or intelligence community projects or research involving Soy for any purpose, and if so, what was its nature?  Can you point me to references that discuss it?

   Answer ...     Not as far as we know.  Professor XXXXX told us in a 1998 personal conversation that the US Army knew soy protein was toxic when they put it into C-rations in the Korean war...but as the users had a low survival outlook anyway, a bit more risk was deemed acceptable (That it not quotable without Irv's permission as he was on the Army's project).

 

                        Privately we often wonder if the Gulf War syndromes may have been connected.!

 

                        This is all top-of-the head stuff. More detail would take us hours which we do not at present have.

                        Cheers Dick.

 

Mr. H. Michael Sweeney ends with saying ... ”Regardless of, if you have any answers on the above that I might find useful, I have a couple of other people who would likely be quite interested in your material, and who might be better suited to helping to promote it on their Web sites.  If you DO have some useful answers, that list will be longer.  I'll make gentle inquiries and suggest they contact you directly.  One is local, and I'll give them the packet, (soy research paper and soy pamphlet), you sent me to reduce your expenses (lot of work put into it, too - great job!) ...”

 

Best , Harry .

                                                                                                                                                                                                                        ... / 15

- 15 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

 

----- Original Message -----

From: Valerie & Richard James , Soy Online Service

To: Tinawinwood@XXXXXXXX

Cc: Mike

Sent: Monday, December 15, 2003 4:47 PM

Subject: Re: 3 generations of soy problems  

 

Hello Tina.  We help the  www.soyonlineservice.co.nz webmaster with his mail. Thank you for your input, though we are really shocked to hear this.  However it is not the first time by any means, and by 1993 we knew that the reproductive system effects of soy in the diet could carry down at leat three generations.  A CANADIAN ASSOCIATE OF OURS HAD FOLLOWED IT IN DAIRY COWS FOR FIVE GENERATIONS BY 1995.

 

For the good of future generations of your family  you should all try  to avoid all exposures to estrogenic foods.  ( See SOS guidance ) ... and this includes soy oil, alfalfa, and flaxseed. Brassicas should be thoroughly cooked

 

Your comments about "news" are a bit sad as, without being totally paranoid we can guarantee that most major media have an embargo on criticising this industry.  We know of countless tales that have been written by journos who think as you do, but have ended up in the Editor's/ Publishers " too hot " bins.  Text is the gray stuff between adverts......and if an industry  like  this  blacklists a publication, the effects  on revenue  can be horrendous.  They are also adept  at using the threat of lawsuits.   The one at http://www.soyonlineservice.co.nz/articles/Sanitarium.pdf ... “Teams of Lawyers", (and also at http://www.soyonlineservice.co.nz/files/Havoc.htm ), is just a small example which happened to be reported in a gossip paper. Sanitarium was the pinch-hitter for Protein Technologies, the DuPont subsidiary.  They lost but it cost the radio station's insurers a bunch to make it go away.  Most insurers want to approve publication if the word "sue" etc is mentioned.  As most editors ask that the industry be interviewed too, the industry threatens to sue. We know it as "censorship by insurance clerk." If you go to HOT READING just regard it as a miracle that that much got published.  Before the NZ scientists got started stuff like that did not exist.

     Do your best locally, Best wishes, Valerie.

..............................................................................................................................................................................

 

 

 

 

----- Original Message -----

From: Tinawinwood@XXXXXX 

To: divulge@xtra.co.nz

Sent: Monday, December 15, 2003 1:15 PM

Subject: 3 generations of soy problems  

 

I have been researching the negative effects of soy for several reason, for the past week i have been on a soy based diet and have found that i gained 9 lbs in 7 days, highly unusual for my body, i went online to research if the change in my diet could be the cause and found the information about the ability of soy to depress the thyroid gland,  needless to say I have removed the soy in my diet and am hoping to reverse this sudden weight gain, more importantly my vegan daughter gave birth to a son this october who was born with hypospadias, she researched the cause and only found information saying that the pesitcides in her vegan diet may have been the cause, we now know have reason to believe it was her daily consumption of soy products, her baby was scheduled to be weaned this week from breast milk & be put on soy formula, of course now that will not be the case, my son who was allergic to milk when he was born 29 years ago was put on prescription soy formula and is going for surgery to have his enlarged breasts reduced, my doctor never told me it was not tested back then, and my daughter peditrician just told her last week that soy formula was okay for our grandson....i am so surprised this soy issue is not in the forefront of the news and tests need to be done,

Sincerely, tina winwood 

 

Note: Make sure the label on your vitamins, minerals, and medications says contains no Soy or … contains no Soy ingredients .

                                                                                Pet Food, farm animal foods                                                                                       ... / 16

- 16 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

----- Original Message -----

From: Valerie & Richard James , Soy Online Service

To: Walter Aaron Foster

Sent: Tuesday, December 16, 2003 4:39 PM , (Note: Time Zone differences)

Subject: Re: thank you!

 

Dear Heather,

We are terribly sorry to read this. If you would like to help on a cold winter eve, one way is to forward by email your letter and our reply to every State medical association.  They mostly have sites with a list of Staff and Officials.  Ask them to pass it to their County branches and advise all members.  Just a 5% hit rate may prevent some harm somewhere. 

We've done that before but got absolutely no feedback, so have no idea if it made any difference.

Best Wishes, Valerie.

.............................................................................................................................................................................

 

 

----- Original Message -----

From: Walter Aaron Foster

To: webmaster@soyonlineservice.co.nz , Soy Online Service

Sent: Wednesday, December 17, 2003 4:27 AM

Subject: thank you!  

 

Thank you for the service you are doing by having this site.  As the mother of a wonderful 4 year old boy, I'd like to add my 2 cents regarding the extreme health hazards of soy.   My son  was born  with a  3rd  degree  hypospadias  which required 10...yes ten surgeries to correct.   He had the worst hypospadias a male can have, where his urethra's opening appeared at the base of his genitals.  How did this utter nightmare occur?  Well, little did I know that the DAILY tofu and soy milk I was drinking for the past decade ( I was foolishly a vegan ) was highly estrogenating my already estrogenated body. Healthy women make enough estrogen as it is.  The phyto estrogens disrupted my fetus' development.  I have met other women who had son's with hypospadias and they ate soy daily all during pregnancy.  Enough said. 

Thank you for helping the public realize how detrimental soy is, and that it's really just junk food. Regards, Heather

...........................................................................

 

 

Hypospadia

 

http://www.amershamhealth.com/medcyclopaedia/Volume%20IV%202/HYPOSPADIA.asp 

A congenital malformation of the urethral groove and urethral canal, resulting in an abnormal opening on the ventral penile surface. On physical examination, the external urethral meatus can be found anywhere on the ventral aspect of the penis, from just proximal to its normal location to the perineum. It is associated with failure of normal testicular descent and malformations of the urinary tract ”.

http://health_info.nmh.org/Library/HealthGuide/IllnessConditions/topic.asp?hwid=rt1129 

                because of abnormalities in their chromosomes or endocrine system ”.

 

See below, just some of many abstracts ... DNA damage ... Chromosome fragmentation & errors in Chromosome orientation at http://www.soyonlineservice.co.nz/04immunefunction.htmand NCBI, PubMed, the USA’s National Center for Biotechnology Information.  Over 15 million citations for biomedical articles from the present and going back to the 1950’s ( National Library of Medicine and National Institutes of Health ).

1989 - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2548712&dopt=Abstract .

1998 - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9729267&dopt=Abstract .

1999 - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10086720&dopt=Abstract .

2000 - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10762754&dopt=Abstract .

2002 - http://www.giftinfo.uni-mainz.de/EXCLI/volumes/Vol1/2002volume1pp8-14.pdf .  

                                                                                                                                                                                                                        ... / 17

- 17 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

Want to know why you don’t hear about the many health hazards of Soy ??

Also see pages 105 - 113 of this 144 page Soy Research Paper

 

Example, this  2003 news  research story below  from ... http://alberta.indymedia.org/news/2003/03/6009_comment.php provides  a  clear  and  undeniable  example  of  the  documented  proof  of  the  attempted  and  mostly  successful suppression & cover-up of the truth  about the  harmful  side-effects  to human and animal health  of  BGH  growth hormone in milk.  The same type of cover-up around the world can easily be proven with respect to the information about the harmful side-effects of eating Soy.  This news article and legal ruling shows why 99% of the research and its information on the many health hazards of eating soy does not reach or get past the news media in order to inform the public.  Also see ... “Hidden Danger in Your Milk ?” at ... http://www.foxBGHsuit.com , BGH growth hormone.

 

Some of us know very well that  the goal of the  news media  is about KEEPING NEWS AWAY FROM people.  In the former Soviet Union, folks knew that  their press was controlled.  In North America, it's much worse, because folks THINK that they have a FREE, democratic press, when in fact, the press has been controlled, manipulated, fabricated and distorted for years !!.  It's Brainwashing at its best and most effective !.

 

 

 

Appellate Court Rules Media Can “Legally Lie”

http://alberta.indymedia.org/news/2003/03/6009_comment.php

By Mike Gaddy, Published 02. 28. 03 at 19:31 Sierra Time

 

On February 14, 2003, a Florida Appeals court ruled  there is absolutely nothing “illegal” about lying, concealing or distorting information  by a major press organization.  The court reversed the $425,000 jury verdict in favor of journalist Jane Akre  who  charged  she  was  pressured  by  Fox Television management and  lawyers  to  air  what  she  knew  and documented to be false information.  The ruling basically declares  it is technically not against any law, rule, or regulation to deliberately lie or distort the news on a television broadcast.

 

On Aug. 18, 2000, a 6-person jury was unanimous in its conclusion that Akre was indeed fired for threatening to report the station's pressure to broadcast what jurors decided was “a false, distorted, or slanted” story about widespread use of growth hormone in dairy cows.  Court didn’t dispute the heart of Akre's claim, that Fox pressured her to broadcast a false story to protect the broadcaster from having to defend the truth in court, as well as, suffer the ire of irate advertisers.

 

Fox argued from the first, and failed  on three separate occasions, in front of three different judges, to have the case tossed out on the grounds there is no hard, fast, and written rule against deliberate distortion of the news.  The  attorneys  for  Fox, owned by media baron Rupert Murdock, argued the First Amendment gives broadcasters the right to lie or deliberately distort news reports on the public airwaves.

 

In its six-page written decision, the Court of Appeals held that the Federal Communications Commission position against news distortion is only a "policy," not a promulgated law, rule, or regulation.

 

Fox aired a report after the ruling saying it was "totally vindicated" by the verdict.

......................................................  

See ... http://www.hairyeyeball.net/jotbook/archives/001530.html  "... In other words, in a layman's reading, Fox did not order her to do anything illegal, only something that Fox could get its license yanked for by the FCC. Well, hmmm, actually, come to think of it, that means there's no "law" against it, only a regulatory "rule," and not an "adopted rule."

“The Florida whistle-blower's law at ...

http://www.flsenate.gov/Statutes/index.cfm?mode=View%20Statutes&SubMenu=1&App_mode=Display_Statute&Search_String=&URL=CH0448/Ch0448.HTM , ... specifies that an employee must have been order to break a "law, rule, or regulation."  Once again, fine slicing and dicing, Florida jurists ...".  

                                                                                                                                                                                                                        ... / 18

- 18 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

Want to know “why” you don’t hear about the many health hazards of Soy ??.

Also see pages 105 - 113 of this 144 page Soy Research Paper

… Continued …

 

Appellate Court Rules Media Can Legally Lie

... Continued ...

 

----- Original Message -----

From:  Valerie & Richard James , Soy Online Service

To: Gerald Hernesmaa

Sent: Tuesday, December 20, 2003 2:36 PM ... and ... December 20, 2003 2:38 PM

Subject: Re: “News Media Can Legally Lie” ... The Suppression of Truth Is Now Legal ... how convenient !!.

 

Hi Gerald

We have known this for years.... and in NZ we suffer from Heinz controlling our biggest media empire....Wilson and Horton ...with 42 papers, 53 radio stations and the two biggest magazines in this little country.    Camille Guy suffered from exactly the same treatment here.  Lost her job, was sent to "Conentry" and blackballed.

Dick.

 

                                                                                                                 ... and ... 

Hi Gerald

Further to our reply to this (topic), a Los Angeles lawyer has pointed out to us that - the FDA and its employees have legislative immunity and can lie with no fear of being held accountable.  Which is what they did in approving a “health claims” for soy.

Dick.

            ............................................................................................................

Einstein said, “...the world is a dangerous place to live in, not because of the people who are evil, but because of the people who don’t do anything about it...”.

 

 

 

Soy, The Deadly Stealth Ingredient

Remember to read the ingredient labels on all of the foods you buy !!.

If Soy Isn’t Harmful, Why Is It Hidden ??.

Found in thousands of ... processed ... canned ... frozen ... junk foods ... Vitamins ... Prescription medications ... etc.

 

Hidden soy” ...  where you wouldn't expect to find it, as in ... up to 90 percentage of hospital foods feed to staff, patients, including cancer patients ... even protein drinks served to cancer patients in hospitals and in cancer clinics ... vitamins, minerals, Medications ... liquid in vitamin E capsules ... almost all candy ... regular ice cream ... all regular salad dressings ... mayonnaise ... a variety of restaurant foods including burgers, french fries ... Kentucky Fried Chicken ... store baked chickens ... hamburger meat in food store meat dept.’s ... some canned tuna’s ... airline foods ... large percentage of baked goods like bread, cakes ... fruit drinks ... lard, margarine ... dairy ... whipped cream ... breakfast cereals ... potato, corn chips ... hot dogs ... Baby foods ... diet beverages ... Campbells Soups ... pet foods ... etc.

 

Undeclared soy” ...  Soy that is not listed on the food or medication ingredient labels, as in ... Prescription medications ... vitamins for children and adults ... MSG is from soy... food manufacturers can be careless and neglect, or purposely neglect to mention soy, or the ingredients have changed and the label hasn’t caught up ... cross-contamination caused by soy used in other products produced at the same facility ... soy dust in the air from the bulk bins at health food stores ... trace amount of soy that has rubbed off from a variety of cardboard packaging, (food, non food packaging), in which soy protein isolate has been used as a bonding ingredient.

 

The 8 “Aliases” of soy - (“False names - also known as”) ...  Commonly used ingredients that people don't recognize as being soy are ...Vegetable oil” ... or ... “Vegetable Shortening” ... or ... “textured vegetable protein“ ... or ... “bouillon”.  These may also contain canola, or both soy and canola.  Then there is ... “MSG which is made from soy ... http://www.truthinlabeling.org/ ... Truth In Labeling. Three more names are “Natural Flavoring...Vegetable Flavoring...Hydrolyzed Protein or Vegetable Protein.

Note: Make sure the label on your vitamins, minerals, medications says contains no Soy or … contains no Soy ingredients  ... / 19

- 19 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

Want to know “why” you don’t hear about the many health hazards of Soy ??

Also see pages 105 - 113 of this 144 page Soy Research Paper

... Continued ...

 

 

----- Original Message -----

From: Valerie & Richard James , Soy Online Service

To: Randy Kay and Beatrice Ekwa Ekoko

Cc: Mike

Sent: Sunday, December 21, 2003 12:17 PM

Subject: Re: precocious puberty ?.

 

Hello Beatrice.

We help the webmaster with his mail. Yes, she has been subjected to those risks......in fact both your daughters have been. “Health Canadaknew specifically of this likelihood in December 1995 and ever since have deliberately hidden this information from mothers even though by Canadian law it should have been revealed to you.

 

If you go to ... www.soyonlineservice.co.nz  Hot Reading, you will see an internet link to an essay by the American Enocrine Society called ... "Pseudo Puberty" at ... http://www.emedicine.com/ped/topic1881.htm# .  At page 4 they say that excess soy consumption can cause it.  Our webmaster believes that exposing children to any estrogens is excessive.

 

We suggest you write to your Minister of Health expressing your dismay.

Good Luck Valerie.

................................................................................................................................................

 

 

 

 

----- Original Message -----

From: Randy Kay and Beatrice Ekwa Ekoko

To: webmaster@soyonlineservice.co.nz

Sent: Monday, December 22, 2003 5:04 AM

Subject: precocious puberty?

 

Hello.

from the  age of  18 months, when my daughter weaned herself, up until I discovered a breast bud on her chest at age 51/2 years old, my daughter drunk soy “milk”.  Could this be the reason she started to develop breasts?  She is also very tall for her age(8)

 

She now takes Traditional Chinese Medicine to slow down the development.

 

I also fed my younger daughter soy products from age one, when I was advised not to feed her diary products as she had chronic ear infections.  She stopped at 18 months when we moved and her ear infections cleared up.  I am worried that she too might show signs of early puberty like her sister.

 

Looking forward to hearing from you.

 

Sincerely,

Beatrice Ekoko

Hamilton, Ontario

.......................................................................................................................................................................................

Note: Make sure the label on your vitamins, minerals, and medications says contains no Soy or … contains no Soy ingredients .

                                                                                Pet Food, farm animal foods                                                                                       ... / 20

- 20 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

----- Original Message -----

From: Valerie & Richard James , Soy Online Service

To: Sheila

Sent: Wednesday, June 23, 2004 8:50 PM

Subject: Re: soy/low thyroid connection

 

Hello Sheila

We help the webmaster with his mail. It's good to hear a few doctors are aware of the dangers. Most conventional ones still have the notion that if they have not heard of something, therefore by definition it cannot exist. The God Complex. 

 

This is the definitive work from the FDA's own scientists ...

   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9464451&dopt=Abstract .

1997       Anti-thyroid isoflavones from Soybean; isolation, characterization, and mechanisms of action, Biochem Pharmacol - Nov 1997; 54(10):1087-96, National Center For Toxicological Research, nctr

 

You are recounting classic secondary signs of hypo-thyroidism and your physical and mental health are likely to improve if you avoid all soy (see SOS Guidance) Also be wary of isoflavone supplements, flaxseed, alfalfa and soy oil, all of which are estrogenic and can destabilize your thyroid

 

Good Luck, Valerie

..............................................................................

 

 

----- Original Message -----

From: Sheila

To: webmaster@soyonlineservice.co.nz

Sent: Wednesday, June 23, 2004 5:52 PM

Subject: soy/low thyroid connection

 

I drink about a glass to two glasses of soy milk a day and eat tofu about twice a week. I was diagnosed with hypothyroidism through my acupuncturist in January of 2004 and am on something called Thyrostim. My hair was falling out prior to being put on Thirostim Also, I was depressed and got hot/cold flashes. I am thirty one years old.. My acupuncturist has also put me on a strict alkalizing diet plan, but soybeans and tofu are OK with this diet plan, he says. I even decided to go Vegetarian a month ago. Even though my hair has stopped falling out, I feel moody and depressed and have gained weight and am not even eating that much.

 

Today I visited a natural alternative healing doctor and he told me to stop the Soy altogether because of my thyroid problem. He told me to type in the “Dangers” of Soy on the internet and here I am. This is all news to me. I am actually shocked. I am now going to dump out my soy milk in the fridge and cupboards. I will report back on how I feel in a couple of weeks after being off Soy completely.

 

Sheila in the U.S.

....................................................................................................................

 

i      ;      i

 

Bush’s “Sound Science”, (Is No Science At All), Turning a deaf ear to reality by David Schubert, July 9, 2004, Organic Consumers Association ... http://www.organicconsumers.org/corp/bushscience071604.cfm .

“... Much of the justification for this repression of scientific communication falls under the “Orwellian concept of sound science," which is clearly understood by the scientific community to mean the “misrepresentation” of scientific data to reflect the administration's political and social agendas ... This political manipulation of U.S. science began well below the level of public awareness within days after the current administration took office, 2001. Highly respected scientists on dozens of advisory committees were replaced with individuals who promote "sound science" as defined by industry and the religious right.         

                                                                                                                                                                                                                        ... / 21

- 21 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

  

 

Soy

The Miracle Food or Pandora's Box?

Researched by Gerald, volunteer, Health Action Network Society

Pamphlet http://www.hans.org/

 

 

What has science been telling us? ... What does history reveal?

 

                "Current evidence for the beneficial

                effects of soy requires a full understanding

                of potential adverse effects as well."

                                Dr. D. Doerge, scientist from the National Center for Toxicological Research.

                                The genistein in soy is a Topoisomerase II-poison

 

Quoted here are many of the scientific research studies on soy spanning the years 1907 through to the present.

                                                                                                                                                                                                    Updated: June 2004

 

Soy Blocks Vitamin and Mineral Absorption

 

Studies indicate that soy (organic and non-organic) causes                                    Endocrine-disrupting isoflavones, genistein and daidzein

increased requirements for vitamins E, K, D and B12.                                           are naturally occurring goitrogenic components found in

Phytic acid from SPI blocks the absorption of essential                                        soy. In vitro and in vivo studies document isoflavones

minerals and creates deficiency symptoms of calcium,                                          inhibiting the synthesis of estradiol and other steroid

magnesium, copper, molybdenum, iron, manganese and                                        hormones. Infertility, reproductive problems, thyroid and

especially zinc - in the intestinal tract. (2) This may be                                        liver disease due to dietary intake of isoflavones have been

contributing to the early onset of osteoporosis in Japan,                                      observed for several species of animals including mice,

starting there as early as age 20 versus age 34 in the                                              cheetah, quail, pigs, rats, sturgeon and sheep. (1.a,3,6)

USA. (1b,3) Also test animals fed SPI developed enlarged

organs, particularly the thyroid gland and pancreas, and                                       100 grams of soy protein - the maximum suggested

caused increased deposition of fatty acids in the liver.                                          cholesterol lowering dose - can contain almost 600mg of

                                                                                                                                isoflavones, an undeniably toxic amount. Only 45 mg

Soybeans have one of the highest phytate levels of any                                        of isoflavones taken daily for one month, in pre-

grain or legume. Phytates in soy are highly resistant to                                         menopausal women, reduced hormones needed for

normal phytate-reducing techniques such as long, slow                                         adequate thyroid function. In some of the women, these

cooking. Only long periods of fermentation will greatly                                        effects lingered for 3 months after soy consumption was

reduce soy's phytate levels, but will not eliminate them.                                       discontinued.

.

Soy Has Natural Toxins or Anti-nutrients                                     The Swiss Health Service, in 1992, estimated that 100

                                                                                                                                grams of soy protein provides the estrogenic equivalent of

Soybeans contain potent enzyme inhibitors that block the                                   one birth control pill. (1.a,3,6)

action of trypsin and other enzymes needed for protein

digestion. These inhibitors are not completely deactivated                                    Asians throughout the world have high rates of thyroid

during ordinary cooking. They can produce serious gastric                                   cancer. Japanese researchers reported in 1991 that

distress, reduced protein digestion and create chronic defi-                                   consumption of as little as 30 grams or 2 tablespoons of

ciencies in amino acid uptakes. In test animals, diets high in                                 soybeans per day for only one month resulted in a

trypsin inhibitors also caused enlargement and pathologi-                                     significant decrease in thyroid-stimulating hormone.

cal conditions of the pancreas, including cancer. (1,3,6,8)                                      Japanese and Asians eat soy in very small amounts, as a

                                                                                                                                condiment (seasoning), not as a protein substitute and not

Soy contains haemaglutinin, which is a clot-promoting                                         as a replacement for animal foods. (1.a,3,6,8)

substance that causes red blood cells to clump together,

setting the stage for clogged arteries and stroke.                                                     Continued ...

                                                                                                                                                                                                                       ... / 22

- 22 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

Soy

The Miracle Food or Pandora's Box?

Health Action Network Society

Continued

 

 

Processing of Soy Adds Even More Toxins                                                 Soy Infant Formula    

 

Much soy is acid washed in aluminum tanks, leaching high                                   Daily exposure of infants to isoflavones in soy infant

levels of aluminum into the final product. Nitrites, potent                                    formula is 6 to 11 times higher on body-weight basis than

carcinogens, are formed during spray-drying, and toxic                                         the dose that has negative hormonal side effects in adults

lysinoalanine is formed during alkaline processing. Arti-                                       consuming soy foods. ( 1.a,3,6,8,9 )

ficial flavourings, particularly MSG are added to SPI and

textured vegetable protein (TVP) products to mask their                                      Approximately 25 per cent of bottle-fed children in the US

strong, "beany" taste and to impart the flavor of meat. (3,9)                                                 receive soy-based formula - a much higher per cent than in

                                                                                                                                other parts of the Western world. Toxicologist Dr Mike

Cancer and DNA Damage                                                                      Fitzpatrick estimated that infants exclusively fed soy

                                                                                                                                formula receive the estrogenic equivalent (based on body

Soy is carcinogenic, causing cancer cells to grow and non-                                     weight) of at least 5 birth controls pills per day. By

cancerous tumours to turn cancerous. (3,6,8) Thousands of                                  contrast, almost no phyto-estrogens have been detected in

women are now consuming soy in the belief that it protects                                                 dairy-based infant formula or in human milk, even when

them against breast cancer. Yet in 1996, researchers found                                  the mother consumes soy products.

that women consuming soy protein isolate (SPI) had an

increased incidence of epithelial hyperplasia, a condition                                      In the 1986 Puerto Rico Premature Thelarche Study, the

that preceded malignancies. Genistein and diadzein                                               most significant dietary association with premature sexual

stimulate breast cells to enter the breast cancer cycle.( 3,6,8)                                development was not chicken, as the press reported, but soy

Since 1989, soy has been known to cause DNA damage,                                     infant formula. (1.a)

chromosome fragmentation and errors in chromosome

orientation. (3,6,8) Pregnant women who eat soy products                                  Early maturation in girls is frequently an indicator of

are at an increase risk for breast cancer. (3,4,6,8)                                                   problems with their reproductive system in later life,

                                                                                                                                including failure to menstruate, infertility, breast cancer

Soy advertisers collectively claim lower rates of                                                    and possibly uterine cancer. (3,6,8) Problems in both sexes

reproductive cancers for Japanese and Asians eating soy,                                     associated with soy-based infant formula later in life also

while ignoring the fact that these people also have much                                       include extreme emotional behaviour, immune system

higher rates of cancer of the esophagus, stomach, liver,                                         problems, pituitary insufficiency, irritable bowel syndrome,

pancreas and thyroid, particularly as soy causes these same                                                 asthma, thyroid disorders including thyroid problems in

types of cancer in laboratory test animals. (1,3,6,8)                                              babies and infantile leukaemia. (1.a,3,6,8,9,10)

.

Brain and Nervous System Damage                                                Thyroid Problems

 

Genistein destroys the myelin sheath surrounding the nerves,                              Soy also contains goitrogens - substances that depress

spinal cord, and brain cell tissue...one cause of Alzheimer’s-                                thyroid function. Diffuse goiter and hypothyroidism

Parkinson’s disease, & learning disabilities ADD-ADHD.(3,6,8)                         appeared in some of the subjects and many complained of

                                                                                                                                fatigue, lethargy and constipation, even though their intake

Japanese Americans living in Hawaii show a significant                                        of iodine was adequate. (3,6,8,9,10)

statistical relationship between two or more servings of tofu

a week and accelerated brain aging (atrophy). In another                                       Soy Warning Labels, for Medical Reasons

study, those eating tofu in mid-life experienced greater

incidence of Parkinson’s / Alzheimer's disease, dementia,                                     In 1999, USA's FDA ignored two of their own expert research

lowered cognitive function, and looked older in later life.                                      scientists, Daniel Sheehan, PhD and Daniel Doerge, PhD,

(1.a,3,6,8,9)                                                                                                            who expressed serious concerns regarding the perceived

                                                                                                                                safe use of soy, if soy was to be granted a 'health claim'. In

                                                                                                                                their letter of protest they said, “…it is inappropriate to

 

Note: Make sure the label on your vitamins, minerals, and medications says contains no Soy or … contains no Soy ingredients .

                                                                                Pet Food, farm animal foods

                                                                                                                                Continued ...                                                                ... / 23

- 23 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

Soy

The Miracle Food or Pandora's Box?

Health Action Network Society

Continued

.

Soy Warning Labels, For Medical Reasons                                References: continued

                                Continued

 

allow a health claim for SPI….. it could be                                                             (4.)  Optimal Wellness Center, by Dr. Joseph Mercola, and e-mail

misinterpreted…. the health labelling of SPI for foods need                                   newsletter "eHealthy News you Can Use" - www.mercola.com

to be considered just as would the addition of any                                                (In 'search', type: soy)

‘estrogen' or 'goitrogen' to foods, which are bad ideas.’                                         

Estrogenic and goitrogenic drugs are regulated by the FDA,                                  (5.)  The 1958 "Delaney Amendment" to the USA FDA Reg.s

and are taken under a physician's care. Patients are                                               prohibits the use of any food additive if it is found to cause

informed of risks, and are monitored by their physicians for                                cancer in any animal species or man, at any dose level.

evidence of toxicity. No similar safeguards are in place for                                    - http://www.pcdf.org/meadows/delaney.htm .

foods, so the public will be put at potential risk from soy

isoflavones in SPI without adequate warning and                                                  (6.)  Soy OnLine Service, SOS, are a small group of private citizens

information.” (7) Vetetable oil is no longer vegetable oil, it                                    from New Zealand, the United States and the United Kingdom.

is either soy, canola, or both. (1a,3,4,6)                                                                 They have no industry connections and are not funded by any

                                                                                                                                outside interest groups. Their mission is to uncover truths about

The soy industry “applied twice and was turned down                                        soy and to provide consumers with an alternative opinion to the

twice” on both of its applications to the USA’s FDA for                                     information generated from the soy industry.

“GRAS (Generally Recognized as Safe)” status for soy                                        - http://www.soyonlineservice.co.nz/ .

protein because of soy’s carcinogenic properties and                                           

soy has not been given “Pre-Market Approval” for use                                        (7.)  USA Scientists Protest Soy Approval, FDA Lay Out

in our food.  Also, soy is in breach of, in violation of,                                           Concerns. Researchers, Daniel Doerge PhD and Daniel Sheehan

“WHO / CODEX” Food Safety Standards.” It is not even                                    PhD are two of the USA's Food and Drug Administration 's

legal to add it to our food (1a,b,3,4,6)                                                                    experts on soy who signed a Feb. 18, 1999 letter of protest

                                                                                                                                documenting 26 referenced studies that show a link between

Toxic Load means that the risk is a function of dose                                       eating soy and serious health problems.

length, dose strength, and of the physical condition of the                                    -  http://www.mercola.com/2001/jun/30/soy_fda.htm ,

consumer. Reference: "The Dose Makes the Poison: A                                  

Plain-Language Guide to Toxicology," 2nd edition,                                         (8.)  PUBMED - www.ncbi.nlm.nih.gov/PubMed/; with hundreds of

© 1996, by M. Alice Ottoboni. (1a,3)                                                                  scientific abstracts showing serious health hazards from eating soy.

                                                                                                                                DNA damage: “Inhibitory effects of the tyosine kinase inhibitor

A comprehensive information package on soy is available                                    genistein on mammalian DNA topoisomerasell.” (Sept. 15, 1989)

from The Health Action Network Society - www.hans.org                              Causes cancer cells to grow: “Phytoestrogen interaction with

                                                                                                                                estrogen receptors in human breast cancer cells.” (Nov. 1978)

                                                                                                                                         Abstracts … http://www.soyonlineservice.co.nz/07abstract.htm .

References:                                                                                                        Osteoporosis … http://www.soyonlineservice.co.nz/03toxins.htm .

                                                                                                                                         Infertility … http://www.soyonlineservice.co.nz/04infertility.htm .

The small numbered footnotes 1-72 correspond to the studies,                              Birth Defects … http://www.soyonlineservice.co.nz/04birthdefects.htm

articles and the legislation referenced in (1.a) by Weston A.                              Cancer … http://www.soyonlineservice.co.nz/04cancer.htm .

Price Foundation. - www.westonaprice.org . Also see its                                      DNA damage www.soyonlineservice.co.nz/04immunefunction.htm . 

update (1.b) Both are © 2000 by S Fallon and MG Enig, PhD                               Brain             www.soyonlineservice.co.nz/04cognitivefunction.htm

 

(1.a.)  "Newest Research on Why You Should Avoid Soy"                             (9.) The Doctor Within ... “The Magic Bean? Soy-Taintly Not !,”

- www.mercola.com/article/soy/avoid_soy.htm , and                                            - http://thedoctorwithin.com/index_fr.php?page=articles/magic_bean.php .

                                                                                                                                Soybean-Bad - http://www.rogerkyoung.com/old/soybean.html .

(1.b.)  "Tragedy and Hype: The 3 rd International Soy                                 

Symposium,"                                                                                                        (10.) “FDA Poisonous Plant Database” Research on the toxic properties

- www.westonaprice.org/soy/tragedy.html .                                                          and effects of plants & plant parts. Going way back to 1907, see # 184

                                                                                                                                Soy in search, http://vm.cfsan.fda.gov/~djw/pltx.cgi?QUERY=SOY .

(2.)  The Gerson Institute, 1572 Second Avenue, San Diego,                            

California 92101, Phone; 619 685 5353 - www.gerson.org/ .                 (11.) “Uterine Adenocarcinoma in Mice Treated Neonattally with

                                                                                                                                Genistein,” June 1, 2001, Cancer Research, Abstract,

(3.)  Soy – Abundance of Health Hazards,                                                         - http://cancerres.aacrjournals.org/cgi/content/abstract/61/11/4325 .

- http://www.mayanmajix.com/soy_summary.pdf one page Summary

- http://www.mayanmajix.com/soy01.html Full 144 page HTML                                                    … End …                                 ... / 24

- 24 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/,

( Also see … http://www.mayanmajix.com/soy.html -- Health Articles - Soy )

.                                                                 Soy - Abundance of Health Hazards                        (( healthwise933@shaw.ca ))

.                                                                                                                                                       Gerald & Deanna - ( Deonaa )

.                           

Soy - Vegetable Protein % Chart

Nutritive Value of American Foods in Common Units

USDA Agriculture Handbook No. 456

.                       

Fruits

     Lemons ... … . … … 16       Strawberry 8       Apricot 8       Watermelon 8      Papaya   6       Grapefruit . … 5

     Honeydew melon 10       Blackberry 8       Grape .. … 8       Tangerine .. … 7       Pear … … 5       Pineapple… … 3

     Cantaloupe … … …   9      Cherry .. … … 8       Orange8        Peach … … … 6       Banana 5       Apple. … … … 1

 

 

Vegetables

Spinach … … … … … … 49                Cauliflower … … … … 40                Green beans ... … … 26                     Tomatoes … ... … 18

New Zealand Spinach . … 47                Mustard Greens … . … 39                Cucumbers … ... . … 24                     Onions … … ... … 16

Watercress … … … … … 46              Mushrooms … … … … 38               Dandelion Greens 24                    Beets … … . … … 15

Kale … … … … … . … … 45               Chinese Cabbage. … … 34               Green Pepper … . … 22                     Pumpkin … ...  12

Broccoli … … … … … … 45            * Lettuce … Parsley .. … 34                Artichokes … … . … 22                    Potatoes .. ... … … 11

Brussels Sprouts. … … … 44             Green Peas … … … … 30                Cabbage … … … … 22     Yams … … .. … … 8

Turnip Greens / Collards  43               Zucchini … . … . … …  28                Celery / Eggplant … 21                     Sweet Potatoes . … 6

 

 

                        Legumes                      Grains              Nuts & Seeds

                                       Soybean sprouts . … … 54                         Wheat germ … . … 31                       Pumpkin seeds … … 21

(Pick non-Soy type)   Mungbean sprouts .. … 43                          Rye … … ... … . … 20                        Sunflower seeds .. … 17

                                       Soybean curd (tofu)  … 43                          Wheat, hard red 17                        Walnuts, black … … 13

                                       Soy Flour .. … … … … 35                         Wild rice … . … … 16                       Sesame seeds … .. … 13

                                       Soybeans ... … … … … 35                         Buckwheat … ..  15                       Almonds … … … … 12

                                       Soy sauce .. … … … … 33                         Oatmeal … .. … … 15                        Cashews … … … … 12

                                       Broad beans … .. … … 32                          Millet … … . … … 12                        Filberts ... … . … …   8

                                       Lentils … … … .. … … 20                         Barley … ... . … … 11

                                       Split peas … … .. … … 28                         Brown rice … .. …   8

                                       Kidney beans ... . … … 26

                                       Navy beans … .. . … … 26          Note Protease ( Enzyme ) inhibitors in Soy - block protein digestion, pg. 84

                                       Lima beans … … … … 26                         Remember, Soy is a very Low quality protein, and it is not very well

                                       Garbanzo beans ... .. … 23                          absorbed by the body.  The actual amount of usable protein in soy is about

                                                                                                                50 % of what it says to the Left, which is then from 16 % to 27 %.

.

More - Safe - Alternatives

Instead of Cow’s milk or Soy Milk … try using Almond milk” -- “Oat milk” -- “Rice milk.   Best to add “Organic” Maple Syrup to Rice milk because that will help make up for its’ low mineral content.  This is especially very, very important for babies children pregnant women cancer patients the elderly.  Note: MSG - is also made from soy … http://www.truthinlabeling.org/.

.   

Be careful … be careful !! … Be careful I said … Be careful !!.  Vegetable oil has not been real Vegetable Oil, that is, actually made from a variety of vegetables, NOT including soy, since early 1970’s.  Since then, it has been either Soy” or “Canola” or both, and it rarely includes cottonseed, peanut, palm oil.  Genistein in soy is proven to be and is classified as a Topoisomerase II-poison.  Use safe Omega-3 oils … cold press 100 % Extra Virgin Olive Oil … Avocado … Coconut Oil … Organic Butter … safe Fish oil.  Flax has been scientifically proven to causes prostate cancer cells to grow, and to be a poisonous plant since 1850.  It is listed along with Soy and Canola in the US FDA’s - Poisonous Plant and Plant Part database, at … http://www.cfsan.fda.gov/~djw/plantox.html. To protect yourself and the ones you Love ... read the ingredient labels on all of the food you buy, switch brands as necessary. Remember, when eating out at restaurants hotels parties hospitals, etc they do not list the ingredients in their food.  Note: Make sure the label on your vitamins, minerals, medications says ... contains no Soy ... or ... contains no Soy ingredients    .../ 25

- 25 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

Soy Isoflavone - PubMed Abstracts

... Short List ...

NCBI … http://www.ncbi.nlm.nih.gov/pubmed/

 

 

See ... Page 74.

1.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9731492&dopt=Abstract .

1998       “Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo,” – Hsieh C.Y., Santell R.C., Haslam S.Z., Helferich W.G., Cancer Res 1998 Sep 1 58:17 3833-8.

“... Genistein causes ... the proliferation of cultured human breast cancer cells ...”

Page 49.

2.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11577007&dopt=Abstract .

2001       “Dietary genistin stimulates growth of estrogen-dependent breast cancer tumors similar to that observed with genistein,” – Allred C.D. and others, Carcinogenesis 2001 Oct;22(10):1667-73.

Stimulates estrogen-dependent breast cancer cell growth ... removal of genistein from diet caused tumors to regress ... Genistin is converted to genistein by human saliva.

Page 42.

3.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10086720&dopt=Abstract .

1999       “Infantile leukemia and soybeans–a hypothesis,” – Abe T., Leukemia 1999 Mar;13(3)317-20.

                                DNA strand breaks ... Infantile Acute Leukemia (IAL) .

Page 44.

4.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10762754&dopt=Abstract .

2000       “Genistein induces apoptosis and topoisomerase II-mediated DNA breakage in colon cancer cells,” – Salti G.I. and others, Eur J Cancer 2000 Apr;36(6):796-802.   

DNA breakage in colon cancer cells occurred within 1 hour of treatment with genistein.

Page 40.

5.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9848512&dopt=Abstract .

1998       “Effects of soy-protein supplementation on epithelial proliferation in the histologically normal human breast,” – McMichael-Phillips D.F. and others, Am J Clin Nutr 1998 Dec;68(6 Suppl):1431S-1435S.

The proliferation rate of breast lobular epithelium significantly increased after just 14 days of soy supplementation ...thus short-term dietary soy containing isoflavone levels found in modern soy foods stimulates breast proliferation.

Page 47.

6.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11694625&dopt=Abstract .

2001       “Physiological concentrations of dietary genistein dose-dependently stimulate growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in athymic nude mice,” – Ju Y.H. and others, J Nutr 2001 Nov;131(11):2957-62.  

                                Genistein stimulated breast tumor growth and cell proliferation in mice in a dose-responsive manner.

Page 50.

7.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11250801&dopt=Abstract .

2001       “Cross-species and interassay comparisons of phytoestrogen actions,” – Whitten P.L. and Patisaul H.B., Environ Health Perspect 2001 Mar;109 Suppl 1:5-20.  

“In vivo data show that phytoestrogens have a wide range of biologic effects at doses and plasma concentrations seen with normal human diets.  Significant in vivo responses have been observed in animal & human tests for ... bone ... breast ... ovary ... pituitary ... vasculature ... prostate and serum lipids. . . . Steroidogenesis and the hypothalamic-pituitary-gonadal axis appear to be important loci of phytoestrogen actions, but these inferences must be tentative because good dose-response data are not available for many end points.”

Page 90.

8.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3559747&dopt=Abstract .

1987       “Absorption of zinc from soy protein meals in humans,” – Sandström B., Kivistö B., & others J Nutr 1987 Feb 117:2 321-7.

Osteoporosis...Lower Zinc absorption...Soy is very high in Phytic Acid...Soy prevents the absorption of essential minerals

                                                                                                                                                                                                                        ... / 26

- 26 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

Soy Isoflavone - PubMed Abstracts - Short List

... continued ...

 

 

See ... Page 52.

9.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11980635&dopt=Abstract .

2002       “Dietary genistein negates the inhibitory effect of tamoxifen on growth of estrogen-dependent human breast cancer

                (MCF-7) cells implanted in athymic mice,” – Ju Y.H. and others, Cancer Res 2002 May 1;62(9):2474-7.  

The use of “dietary isoflavone supplements” by postmenopausal women “with breast cancer” is increasing.

Dietary genistein negated or overwhelmed the inhibitor effect of tamoxifen on MCF-7 tumor growth, lowered E2 levels in plasma, and increased expression of E-response genes (e.g., pS2, PR, and cyclin D1) in ovariectomized and athymic mice.

“Therefore, Caution Is Warranted for postmenopausal women consuming dietary genistein while on TAM therapy for E-responsive breast cancer.”

Page 52.

10.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11993873&dopt=Abstract .

2002       ““Something from “nothing” - - eight weak estrogenic chemicals combined at concentrations below NOECs produce significant mixture effects,” – Silva E. and others, Environ Sci Technol 2002 Apr;36(8):1751-6.  

Xenoestrogens including genistein were tested in combinations.   The results were additive, producing significant effects when combined at low concentrations.  “Our results highlight the limitations of the traditional focus on the effects of single agents.  

Hazard assessments that ignore the possibility of joint action of estrogenic chemicals will almost certainly lead to significant underestimations of risk.”

Page 49.

11.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11431339&dopt=Abstract .

2001       “Soy diets containing varying amounts of genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dose-dependent manner,” – Allred C.D. and others, Cancer Res 2001 Jul 1;61(13):5045-50.  

Depending on processing, soy protein isolates, SPI’s, very widely in concentrations of genistein.

                Soy protein isolates containing increasing concentrations of genistein stimulate the growth of “estrogen-dependent breast cancer cells in vivo in a dose-dependent manner.

Page 52.

12.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12060828&dopt=Abstract .

2002       “Goitrogenic and estrogenic activity of soy isoflavones,” – Doerge D.R. and D.M. Sheehan, Environ Health Perspect 2002 Jun;110 suppl 3:349-53.  

Although safety testing of natural products, including soy products, is not required, the possibility that widely consumed Soy products may cause harm in the human population via either or both estrogenic and goitrogenic activities is of concern.

Page 55.

13.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12113884&dopt=Abstract .

2002“    A pilot study of the effects of phytoestrogen supplementation on postmenopausal endometrium,” – Balk J.L. and others, J Soc Gynecol Investig 2002 Jul-Aug;9(4)238-42.  

This was a ... double-blinded ... randomized ... placebo-controlled trial ... comparing the effects of 6 months of dietary phytoestrogen supplementation versus placebo in postmenopusal women.

“Phytoestrogens did not cause stimulation of the endometrium. Insomnia was more frequent over the 6-month study in the soy group, whereas - hot flushes, night sweats and vaginal dryness improved from baseline in the placebo group but not in the soy group.”

Page 32.

14.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2548712&dopt=Abstract .

1989       “Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II,” – Markovits J. and others, Cancer Res 1989 Sep 15;49(18):5111-7.  

Genistein stimulates double strand DNA breaks. 

                                                                                                                                                                                                                        ... / 27

- 27 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

Soy Isoflavone - PubMed Abstracts - Short List

... continued ...

 

 

See ... Page 32.

15.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3297906&dopt=Abstract .

1987       “Dietary estrogens - a probable cause of infertility and liver disease in captive cheetahs,” – Setchell K.D. and others,  Gastroenterology, 1987 Aug;93(2): 225-233.

Captive adult cheetahs consuming approximately 50 mg soy isoflavones per day from soy-based feed develop reproductive failure and liver disease.

When chicken-based feed was substituted for soy-based feed, liver function improved. “. . . the relatively high concentrations of phytoestrogens from soybean protein present in the commercial diet fed to captive cheetahs in North American zoos may be one of the major factors in the decline of fertility and in the etiology of - liver disease - in this species.   The survival of the captive cheetah population could depend upon a simple change of diet by excluding exogenous estrogen.”

Page 31.

16.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=570914&dopt=Abstract&itool=iconabstr .

1978       “Phytoestrogen interaction with estrogen receptors in human breast cancer cells,” – Martin M.P. and others, Endocrinology 1978 Nov;103(5):1860-7.

Phytoestrogens “translocate the cytoplasmic estrogen receptor & bind to unfilled nuclear estrogen receptors in whole cells. Bound nuclear receptors are then processed in a manner similar to estradiol in a step which rabidly decreases total cellular estrogen receptors. Phytoestrogens are also biologically active; they can markedly enhance tumor cell proliferation.”

 

 

Frying The Brain With Soy

;

Page 64.

17.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10763906&dopt=Abstract .

2000       “Brain aging and midlife tofu consumption, – White L.R., Petrovitch H., Ross G.W., and others, J Am Coll Nutr. 2000 Apr;19(2):242-55.,

RESULTS: Poor cognitive test performance... enlargement of ventricles... low brain weight... were each significantly & independently associated with higher mid-life tofu consumption.

Statistically significant associations were consistently demonstrated in linear & logistic multivariate regression models.

CONCLUSIONS: In this population, higher midlife tofu consumption was independently associated with I hope you and your family find it interesting and useful ... indicators of cognitive impairment and brain atrophy in late life.

Page 63.

18.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12566171&dopt=Abstract .

2003       “Soya phytoestrogens change cortical and hippocampal expression of BDNF mRNA in male rats,” – File SE, Hartley DE, Alom N., Neurosci Lett 2003 Feb 27;338(2):135-38.,

... Significant reductions were found in brain-derived neurotrophic factor (BDNF) mRNA expression in the CA3 and CA4 region of the hippocampus and in the cerebral cortex in the rats fed the diet containing phytoestrogens, compared with those on the soya-free diet.

Page 63.

19.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9387865&dopt=Abstract .

1997       “Brain-derived neurotrophic factor is reduced in Alzheimer's disease,” – Connor B, Young D, Yan Q, and others., Brain Res Mol Brain Res., 1997 Oct3;49(1-2):71-81.,

... BDNF mRNA is reduced in the human Alzheimer's disease hippocampus and temporal cortex, and suggest that a loss of BDNF may contribute to the progressive atrophy of neurons in Alzheimer's disease.

 

                                                                                                                                                                                                                        ... / 28

- 28 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

Soy Isoflavone - PubMed Abstracts - Short List

... continued ...

 

 

See ... Page 43.

20.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11910681&dopt=Abstract .

1999       “Hot flushes and other menopausal symptoms in relation to soy product intake in Japanese women,” – Nagata C. and others, Climacteric 1999 Mar;2(1):6-12. 

Intake of fermented soy products was found to reduce the severity of hot flashes in Japanese women, but not total soy intake (from unfermented soy products such as are found in western diets).

                                This study is included because it contradicts assertions that Japanese women do not suffer from hot flashes.

      Side note:  All the promotions for soy for menopausal relief were because Japanese women do not have a word

                                                         for it. All that means is they don't talk about them. They have them all right. Look at this research. 

Only fermented soy products had a minor effect and that was just with in the margin of statistical error (ie.) it was more likely to be random chance !.

Page 56.

21.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12738504&dopt=Abstract .

2003       “Effect of soy-derived isoflavones on hot flushes, endometrial thickness, and the pulsatility index of the uterine and cerebral arteries,” – Penotti M., Fabio E., and others, Fertil Steril 2003 May;79(5):1112-1117.,

To determine the effect of soy-derived isoflavones on hot flushes, endometrial thickness, and the vascular reactivity of uterine and cerebral arteries.  Double-blind, randomized, placebo-controlled trial.  Healthy volunteers in an academic research environment.

Daily administration of 72 mg of soy-derived isoflavones is no more effective than placebo in reducing hot flushes in postmenopausal women. It also has no effect on endometrial thickness or PI of the uterine and cerebral arteries

Page 58.

22.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12704663&dopt=Abstract .

2003       “Cell-transforming activity and mutagenicity of 5 phytoestrogens in cultured mammalian cells,” – Tsutsui T, Tamura Y, Yagi E, and others, Int J Cancer 2003 Jun 20;105(3):312-20.,

For the simultaneous assessment of in vitro carcinogenicity and mutagenicity of phytoestrogens, the abilities of 5 phytoestrogens, daidzein, genistein, biochanin A, prunetin, and coumestrol, to induce cell transformation and genetic effects were examined using the Syrian hamster embryo (SHE) cell model.

Our results provide evidence that... genistein... coumestrol... daidzein ... biochanin A  ... induce cell transformation in SHE cells and that the transforming activities of these phytoestrogens correspond to at least 2 of the mutagenic effects by each phytoestrogen, i.e., gene mutations, chromosome aberrations, aneuploidy or DNA adduct formation, suggesting possible involvement of mutagenicity in initiation of phytoestrogen-induced carcinogenesis.

Page 37.

23.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8896889&dopt=Abstract .

1996       “Stimulatory influence of soy protein isolate on breast secretion in pre-and postmenopausal women,” – Petrakis N.L. and others, Cancer Epidemiol Biomarkers Prev  1996 Oct;5(10):785-794. 

The authors noted that “the findings did not support our a priori hypothesis” that soy protected Asian women against breast cancer. 

Instead, this pilot study indicates that “prolonged consumption” of soy protein isolate has a “stimulatory effect“ on the premenopausal female breast ... These findings are suggestive of an estrogenic stimulus from the isoflavones genistein and daidzein contained in soy protein isolate.

Page 42.

24.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10425307&dopt=Abstract .

1999       “Maternal exposure to genistein during pregnancy increases carcinogen-induced mammary tumorigenesis in female rat offspring,” – Hilakiviv-Clarke L., others, Oncol Rep 1999 Sep-Oct;6(5):1089-95. 

Increased breast tumor risk from foetal exposure to Soy ... Carcinogen-induced mamary tumorigenesis.

 

 

                                                                                                                                                                                                                        ... / 29

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Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

April 2006

 

 

 

Hidden Harm

The Evidence ... Long Known, Ignored, and still Denied

.

(120 + 85(+) Extra) Short Summaries of Abstracts

and plus Toxic, Poisonous “Plant Sterols”

from

Isoflavone Studies

1907 - 1953 – 2004

(+)Plus “The Precautionary Principle

Error on the side of caution The obligation to prevent harm

 

 

Please note: the i does not indicate any magnitude of importance scientifically, it only indicates order of  importance to me, Gerald Hernesmaa, healthwise933@shaw.ca .  

 

1907     ( See page 83 of this paper) for this abstract from the list in US FDA’sPoisonous Plant Database”.  For a lot more abstracts between 1907 and 2004 not listed here, click on ….http://www.cfsan.fda.gov/~djw/pltx.cgi?QUERY=soy , ( see item # 165 ).

 

1925    "Experimental rickets: The effect of cereals and their interaction with other factors of diet and environment in producing rickets", — Mellanby, Edward., Journal of the Medical Research Council 93:265, March 1925, This research footnote (#20) is from the essay, “The Newest Research On Why You Should Avoid Soy,” — Fallon S., Enig M.G., April 2000, Weston A. Price Foundation

 

 

   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=13076231&dopt=Abstract .

1953    “Estrogenic Activity of Isoflavone Derivatives Extracted and Prepared from Soybean Meal,” – Cheng C. and others, Science 1953;118:164-5.  

Feeding 2.5 or 5.0 mg of either genistein or genistin per day to the mouse resulted in increased uterine weights.

 

 

   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14368363&dopt=Abstract .

1954    “Effect of Genistin on Reproduction of the Mouse,” – Carter and others, J Nutr 1954;55:639.

— Exposure to the phytoestrogen genistin caused significant advancement of the vaginal opening and a decrease in the number of litters born.

 

 i  i  i

   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=13346413&dopt=Abstract .

1956    “Effect of Genistin on Growth and Development of the Male Mouse,” – Matrone G. and others, J Nutr, 1956, 235-240.

— “The evidence presented indicates that genistin at certain dose levels has a detrimental effect on survival, growth rates and spermatogenesis in mice. . . the higher dose appeared to be lethal. It appears that genistin in relation to its estrogenic activity has a greater depressing effect on growth than does stilbestrol.”

 

 

1963    “Biological Responses of Young Rats Fed Diets Contain Genistin or Genistein,” – Magee A.C., J Nutr 1963;80:151.

— A dietary level of 0.5% genistin or genistein resulted in significant decreases in weight gain and in the weights of kidneys and spleen.                                                                                                                                                     ... / 30

- 30 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

 

                - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=PubMed .

1963    “Estrogenic Effects of Genistein and Coumestrol Diacetate,” – Noteboom and Gorski, Endocrinology, 1963 Dec., 73736-9. No abstract available.

— “It is quite likely that plant estrogens perform the same function as estradial in triggering anabolic responses.  The results of these experiments indicate that certain of the nonsteroidal estrogenic compounds are capable of stimulation of labelled precursors into protein, lipid and ribonucleic acid in the cells of the rat uterus.”

 

 

 i  i  i

   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=PubMed .

1966    “The interaction in the Immature Mouse of Potent Estrogens with Coumestrol, Genistein and other utero-Vaginotropic Compounds of Low Potency,” – Folmon Y. and others, J Endrocrin 1966 ;34:215-225. No abstract available.

— Phytoestrogens such as genistein are said to be of “weak” potency. This study found that sometimes these estrogens were additive at very small doses and appeared to be antagonistic at higher doses. “Genistein gave a steep dose-response curve with high responses (uterus weight near 45 grams) typical of the most potent estrogens.”

 

 

 i  i  i , i  i  i , i - can cause reproductive disorders in females.  

1967    “The oestrogenic activity and metabolism of certain isoflavones in sheep,” – Braden and others, Australian Journal of Agricultural Research 1967, 18:335-348.

— “Some plants that are commonly grazed nevertheless contain substances that are harmful to the animals ingesting them and one group of such compounds (phyto-estrogens) can cause reproductive disorders in females.”

 

 

 

1972    “Steroid and Phytoestrogen Binding to Sheep Uterine Receptors in Vitro,” – Shutt D.R., J Endocrin 1972;52:299-305.

— Phytoestrogens were found to compete with estradiol for binding sites. “A full estrogenic response is elicited only when they are given in repeated frequent doses, which may be necessary to maintain a high blood concentration.”

 

 

 i  i  i , i  i  i , i

1976    “Phytoestrogens: Adverse effects on reproduction in California Quail,” – Leopold A.S. and others, Science, 1976 Jan 9;191(4222): 98-100.

— During dry years, phytoestrogens, including genistein, are produced in the leaves of stunted desert annuals. When ingested by California quail, these compounds apparently inhibit reproduction and prevent the  production of young that will not have adequate food. In a wet year, forage grows vigorously and phytoestrogenic substances are largely absent. Quail then breed prolifically and the abundant seed crop carries the enlarged population through the winter.

 

 

 i  i  i , i  i  i , i  i  i , i  i  i - developed enlarged goiters and malignant thyroid tumors.

   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1035180&dopt=Abstract .

1976    “Development of malignant goiter by defatted soybean with iodine-free diet in rats,” – Kimura S. and others, Gann 1976, 67:763-765.

— Iodine-deficient rats fed defatted soybean for 6 to 12 months developed enlarged goiters and malignant thyroid tumors.  Thyroid enlargement was inhibited with the addition of small amounts of iodine to the diet.

 

 

                                                                                                                                                                                                                        ... / 31

- 31 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

 i  i  i , i  i  i , i - reduce fertility 

1976    “The Effects of Plant Estrogens in Animal Reproduction,” – Shutt D.R.,  Endeavour 1976:110-113.

— “In high concentrations, a weak plant estrogen can exert a significant estrogenic effect in the animal and can product hormonal imbalance ... when high blood concentrations are maintained, they can exert a maximal estrogenic effect ... From the wider viewpoint of evolution, it is interesting that compounds have evolved in plants that not only give the plant some protection from pathogens, but also reduce fertility of animals ingesting the plant.”

 

 

 i  i  i , i  i  i , i - fertility impairment

   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1066275&dopt=Abstract .

1976    “Occurrence of Anabolic Agents in Plants and their Importance,” – Lindner H.R., Environment Quality Supplement 1976;5:151-158.

— “Coumestrol and genistein stimulate estradiol in stimulating macromolecular changes in the uterus. The biological effects of clover estrogens responsible for fertility impairment appear to be multiple.”

 

 

 i  i  i , i  i  i , i  i  i , i  i  i - Phytoestrogens can markedly enhance tumor cell proliferation

   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=570914&dopt=Abstract .

1978    “Phytoestrogen interaction with estrogen receptors in human breast cancer cells,” – Martin M.P. and others, Endocrinology 1978 Nov;103(5):1860-7.

— Phytoestrogens can markedly enhance tumor cell proliferation.  The interactions of phytoestrogens with estrogen receptors were studied in the human breast cancer cell line, MCF-7.

— The compounds tested were ... coumestrol ... genistein ... and formononetin and the mycotoxins, zearalenone and its reduced derivative, zearalenol. All but formononetin compete for binding of [3H]-estradiol to unfilled cytoplasmic estrogen receptor or unfilled nuclear estrogen receptor sites.

— The phytoestrogens are also biologically active; they can markedly enhance tumor cell proliferation.

— In summary ... phytoestrogens interact with the estrogen receptors of human breast cancer cells in culture and, therefore, may affect estrogen-mediated events in these cells.

— Phytoestrogens “translocate the cytoplasmic estrogen receptor and bind to unfilled nuclear estrogen receptors in whole cells. Bound nuclear receptors are then processed in a manner similar to estradiol in a step which rabidly decreases total cellular estrogen receptors. The phytoestrogens are also biologically active; they can markedly enhance tumor cell proliferation.”

 

 

1980    “Oestrogenic activity of soya-bean products,” – Drane H.  M. and others, Food Cosmetics and Technology 1980 Aug ;18(4): 425-427.

— Sixteen samples of soya-containing products were examined after the commercial mouse diet was found to have estrogenic effects in laboratory mice, and compared with the effects of DES on the weight of the mouse uterus. All samples demonstrated estrogenic activity. The researchers attributed the effects as equivalent to 16 ppm and 24 ppm DES in the two samples of human food used. 

 

 

 i  i  i , i  i  i , i  i  i , i  i  i - has been know for more than half a century

   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=4018320&dopt=Abstract .

1985    “Naturally Occurring Estrogens in Food - - A Review,” – Jones and others, Journal of Food Additives and Contamination 1985;2(2):73-106.

   ; i ;  — That estrogen compounds in plants “induce estrus in immature animals and interfere with normal reproductive processes has been know for more than half a century. Consideration should be taken of any medium or long-term changes in dietary habits which might be expected to increase the intake of such phytoestrogens. The increasing use of vegetable proteins in general and in particular and the introduction of soy milk products for infant feeding are two such examples.”             

 

                                                                                                                                                                                              ... / 32

- 32 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

 i  i  i , i  i  i , i 

1985    “Non Steroidal Estrogens of Dietary Origin,” – Setchell K.D., Estrogens in the Environment, John A McLaughlin, ed. Elsivir, 1985:69-83.

— “Since as little as 8 mg of genistein and 10 mg of daidzein are sufficient to initiate uterotrophic effects in mice, it is not surprising that the relatively large amounts of isoflavones present in soy protein will readily explain the previously observed estrogenic effects in animals ... The effects of plant estrogens in man should, however, be of some concern since the newborn infant will be subject to chronic exposure to soya–milk, in some cases for up to two years ... this situation could be considered analogous to sheep grazing on clover.”

 

 

 i  i  i

   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2980380&dopt=Abstract .

1987    “Effects of phytoestrogens on GnRH-induced luteinizing hormone secretion in ovariectomized rats,” – Hughes C.I. Jr., Reprod Toxicol 1987-88;1(3):179-81.

— “The dose potency of genistein appears to be approximately 1/10 that of E2 [estradiol-17 beta] in this system. Phytoestrogens acutely perturb reproductive neuroendocrine function.”

 

 

 i  i  i , i  i  i , i  i  i , i  i  i - liver function improved

                                                                when chicken-based feed was substituted for soy-based feed.

   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3297906&dopt=Abstract .

1987    “Dietary estrogens - a probable cause of infertility and liver disease in captive cheetahs,” – Setchell K.D. and others, Gastroenterology Aug;1993(2): 225-233.

— Captive adult cheetahs consuming approximately 50 mg soy isoflavones per day from soy-based feed develop reproductive failure and liver disease.

— When chicken-based feed was substituted for soy-based feed, liver function improved. “. . . the relatively high concentrations of phytoestrogens from soybean protein present in the commercial diet fed to captive cheetahs in North American zoos may be one of the major factors in the decline of fertility and in the etiology of - liver disease - in this species.   The survival of the captive cheetah population could depend upon a simple change of diet by excluding exogenous estrogen.”

 

 

 i  i  i , i  i  i , i  i  i , i  i  i - double strand DNA breaks.

   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2548712&dopt=Abstract .

1989    “Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II,” – Markovits J. and others, Cancer Res 1989 Sep 15;49(18):5111-7.,  Laboratorie de Pharmacologie Moleculair, URA 158 du CNRS, U 140 de I’NSERM, Institute Gustave Roussy, Villejuif, France.

   ; i ;  — Genistein stimulates double strand DNA breaks.

— Our results show that genistein (a) inhibits the decatenation activity of DNA topoisomerase II and (b) stimulates DNA topoisomerase II-mediated double strand breaks in pBR322 DNA on sites different from those of 4'-(9-acridinylamino)methanesulfon-m-anisidide, etoposide, and 2-methyl-9-hydroxyellipticinium.

— Finally, genistein treatment  of DC-3F cells  results in the occurrence of protein-linked DNA strand breaks as shown by DNA filter elution. Viscometric (lengthening) studies demonstrate that genistein isn’t a DNA intercalator. Genistein is therefore an interesting compound because it induces cleavable complexes without intercalation.

— Taken together, our results show that genistein is an inhibitor of both protein tyrosine kinases and mammalian DNA topoisomerase II. This could be accounted for by the sharing of a common structure sequence between the two proteins at the ATP binding site.

 

 

 

 

                                                                                                                                                                                                                        ... / 33

- 33 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

 i  i  i , i  i  i , i  

1989    “Development and Application of High Performance Chromatographic Method for the Analysis of Phytoestrogens,” – Jones A.E., Jour Sci Food Agric 1989;46:157-164. 

— “It should be emphasized that the effects of long-term low level exposure are unknown ... Vegetarians, vegans and those relying on ‘health’ food preparations from alfalfa, legumes or soya in particular would appear to be likely to regularly consume very much higher levels of estrogens than those estimated for the population at large.

 

 

 i  i  i , i  i  i , i  i  i , i  i  i - DNA cleavage in vitro. 

1990    “Induction of mammalian topisomerase II dependent DNA cleavage by nonintercalative flavonoids, genistein and orobol,” – Yamashita Y. and others, Biochem Pharmacol 1990 Feb 15;39(4):737-44.

— Genistein induced DNA cleavage in vitro. 

 

 

 i  i  i , i  i  i , i  

   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1868922&dopt=Abstract .

1991    “The effects on the thyroid gland of soybeans administered experimentally in healthy subjects,” – Y. Ishizuki and others,  Nippon Naibunpi Gakkai Zasshi 1991, 767: 622-629.  

— Feeding 30 grams (2 tablespoons) soybeans per day for three months to healthy adults receiving adequate iodine intake caused thyroid suppression, especially in the elderly. Hypometabolic symptoms (malaise, constipation, sleepiness) and goiters appeared in half the younger subjects (mean age of 29) and half the older subjects (mean age 61). The symptoms disappeared 1 month after the cessation of soybean ingestion. “These findings suggested that excessive soybean ingestion for a certain duration might suppress thyroid function and cause goiters in healthy people, especially elderly subjects.” Note that 30 grams per day was considered “excessive” by these Japanese researchers.

 

 

 

1991    “Estrogenic effect of dietary soy bean meal on vitellogenesis in cultured Siberian Sturgeon Acipenser baeri,” – Pelissero C. and others, Gen Comp Endocrinol 1991 Sep;83(3):447-57 83:447-457. 

— Sturgeon fed a diet high in isoflavones from soybeans had significantly higher levels of plasma vitellogenin. Vitellogenin is a biomarker for estrogenic effects.

 

 

   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1656271&dopt=Abstract .

1991    “Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors,” – O’Dell T.J. and others, Nature 1991 Oct;353(6344):558-60.

— Long-term potentiation (LTP) in the hippocampus is thought to contribute to memory formation. Tyrosine kinase inhibitors (such as genistein) block LTP.

 

 

 i  i  i , i  i  i , i  i  i , i  i  i - a strong immuno-suppressant

1991    “Evidence that genistein, a protein-tyrosine kinase inhibitor, inhibits CD28 monoclonal-antibody-stimulated human T cell proliferation,” – Atluru S. and Atluru D., Transplantation 1991 Feb;51(2):448-50., Department of Anatomy and Physiology, Kansas State University, Manhattan 66506

       ; i ;                — Genistein blocks the production of T cells, needed for the immune system.

— The authors conclude: “ ... that genistein is a powerful immuno-suppressive agent ...” and suggest that it has a potential use in the treatment of allograft rejection.

 

 

 

                                                                                                                                                                                                                        ... / 34

- 34 -

Dangers of Dietary Isoflavones

at levels above those found in traditional diets

The Risks Of Abandoning “The Precautionary Principle”

by Soy Online Service … http://www.soyonlineservice.co.nz/

“Soy - Abundance Of Health Hazards” http://www.mayanmajix.com/soy01.html

 

 

 

 

 i  i  i , i  i  i , i  i  i , i  i  i - 100 grams of Soy protein = 1 contraceptive pill

   - http://www.mercola.com/article/soy/avoid_soy.htm , Foot Note #53.  

1992    “Bulletin de L’Office Federal de la Santé Publique,”#53. Bulletin de L'Office Fédéral de la Santé Publique, No. 28, July 20, 1992.

— The Swiss Health Service estimates that 100 grams of soy protein provides the estrogenic equivalent of the contraceptive pill.

 

 

 i  i  i , i  i  i , i  i  i , i  i  i - a strong immuno-suppressant

   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1330289&dopt=Abstract .

1992    “Effects of genistein on the growth and cell cycle progression of normal human lymphocytes and human leukemic MOLT-4 and HL-60 cells,” – Traganos F. & others, Cancer Res 1992 Nov 15;52(22):6200-8.,  Cancer Research Institute, New York Medical College, Valhalla 10595.

   ; i ;  — The results suggest that genistein “is expected to be a strong immuno-suppressant.

— Genistein (GEN) is an isoflavone known to inhibit both tyrosine protein kinases and DNA topoisomerase II.

— The effects of GEN on cell proliferation and cell cycle kinetics of human myelogenous leukemia HL-60 and lymphocytic leukemia MOLT-4 cell cultures were studied, and the data were compared to results obtained with normal human lymphocytes stimulated to proliferate with phytohemagglutinin.

 

 

 i  i  i , i  i  i - in all kinds of farm animals ... risk to man cannot be excluded.

   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1387742&dopt=Abstract .

1992    “Validation of Two In Vitro Test Systems of Estrogenic Activities with Zearelenone Phytoestrogens and Cereal Extracts,” – Mayr U., Toxicology 1992;72:135-149.,  Institut fur Tierernahrung, Universitat Hohenheim, Stuttgart, Germany.

— disease ... in all kinds of farm animals ... inherent health risk ... to man cannot be excluded.

— “Ingestion of these compounds causes diseases of the ... reproductive system ... reversible and irreversible infertility ... and abnormal fetal development ... in all kinds of farm animals.

Furthermore, an inherent health risk to man cannot be excluded.” This paper contains graphs showing the crossover of phytoestrogens from estrogenic to antiestrogenic to toxic.

 

 

 i  i  i , i  i  i , i  i  i , i  i  i - http://www.soyonlineservice.co.nz/04immunefunction.htm  .

   - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8393675&dopt=Abstract

1993    “Genistein induces apoptosis in immature human thymocytes by inhibiting topoisomerase-II,” – McCabe M.J. Jr. and Orrenius S., Biochem Biophys Res Commun  1993; 194(2):944-50.

— The toxicity of genistein on human thymus cells was investigated. “Genistein induced marked chromatin fragmentation indicative of apoptosis in human thymocyte cultures.”

 

 

 i  i  i , i  i  i , i